The COVID-19 pandemic era is causing a relevant issue for the health. There is no specific drug able to antagonize the SARS-CoV-2 infection. As a consequence, there is growing interest about potential molecules able to contrast infection. In this regard, HMGB, an alarmin, may play a relevant role in pathogenic mechanisms induced by SARS-CoV-2. As HMGB1 is antagonized by glycyrrhizin, this substance could be potentially useful as ancillary treatment in COVID-19.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851008 | PMC |
| http://dx.doi.org/10.23750/abm.v92iS6.12111 | DOI Listing |
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HMGB1-antagonism exerted by glycyrrhizin could be fruitful against COVID-19.
Acta Biomed
October 2021
International Federation ORL Societies (IFOS) Executive Board members Rome Italy.
The COVID-19 pandemic era is causing a relevant issue for the health. There is no specific drug able to antagonize the SARS-CoV-2 infection. As a consequence, there is growing interest about potential molecules able to contrast infection.
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