Six Sigma is a methodology to diminish variation and errors and improve efficiency, quality, value, and profit, using certain defined steps and statistical analysis. For existing products and services, the DMAIC (Define, Measure, Analyze, Improve, and Control) acronym is used to stand for its steps. For new products and services, the Design for Six Sigma methodology is used. The goal of Six Sigma is to reduce the number of defects to no more than 3.4 for every million opportunities.
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Assessment of mechanical properties and microstructure of Co-Cr dental alloys manufactured by casting, milling, and 3D printing.
J Prosthet Dent
December 2024
Associate Professor, Dental Biomaterials Research Laboratory, Department of Restorative Dentistry, Gerald Niznick College of Dentistry, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:
Statement Of Problem: The mechanical properties and microstructure of cobalt chromium (Co-Cr) alloys should be considered when choosing the best alloy for each clinical situation. More information is needed on the digital manufacturing methods of metals in dentistry, such as computer numerical control (CNC), and direct laser metal sintering (DMLS).
Purpose: The aim of this study was to investigate the effect of the 3 different Co-Cr manufacturing processes on the mechanical properties and microstructure of Co-Cr dental alloys.
Using apparent diffusion coefficient maps and radiomics to predict pathological grade in upper urinary tract urothelial carcinoma.
BMC Med Imaging
December 2024
Department of Radiology, Peking University First Hospital, 8, Xishiku Street, Xicheng District, Beijing, 100034, China.
Background: The apparent diffusion coefficient (ADC) has been reported as a quantitative biomarker for assessing the aggressiveness of upper urinary tract urothelial carcinoma (UTUC), but it has typically been used only with mean ADC values. This study aims to develop a radiomics model using ADC maps to differentiate UTUC grades by incorporating texture features and to compare its performance with that of mean ADC values.
Methods: A total of 215 patients with histopathologically confirmed UTUC were enrolled retrospectively and divided into training and test sets.
Achieving High Standards in Clinical Biochemistry: Integrating Six Sigma, Quality Goal Index (QGI), and Operating Specifications (OPSpecs) for Targeted Quality Enhancement.
Cureus
November 2024
Department of Biochemistry, Pramukhswami Medical College, Bhaikaka University, Anand, IND.
Background Sigma metrics, a cornerstone of quality control (QC) in manufacturing, have been increasingly adopted in analytical processes. In clinical biochemistry labs, Sigma analysis provides insights into the level of QC achieved and identifies deviations from perfection. Methods A prospective-retrospective observational study was conducted at the Central Diagnostic Laboratory of Shree Krishna Hospital between August 2021 and July 2022.
View Article and Find Full Text PDFVoice of a woman: influence of interaction partner characteristics on cycle dependent vocal changes in women.
Front Psychol
December 2024
Department for General Psychology and Cognitive Neuroscience, Institute of Psychology, Friedrich Schiller University, Jena, Germany.
Introduction: Research has shown that women's vocal characteristics change during the menstrual cycle. Further, evidence suggests that individuals alter their voices depending on the context, such as when speaking to a highly attractive person, or a person with a different social status. The present study aimed at investigating the degree to which women's voices change depending on the vocal characteristics of the interaction partner, and how any such changes are modulated by the woman's current menstrual cycle phase.
View Article and Find Full Text PDFUltrasensitive Lateral Flow Immunoassay of Fluoroquinolone Antibiotic Gatifloxacin Using Au@Ag Nanoparticles as a Signal-Enhancing Label.
Biosensors (Basel)
December 2024
A.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Prospect 33, 119071 Moscow, Russia.
Gatifloxacin (GAT), an antibiotic belonging to the fluoroquinolone (FQ) class, is a toxicant that may contaminate food products. In this study, a method of ultrasensitive immunochromatographic detection of GAT was developed for the first time. An indirect format of the lateral flow immunoassay (LFIA) was performed.
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