is an aromatic medicinal herb. It is locally to India and distributed in China, Myanmar, Indonesia, Malaysia, and Thailand. is a Traditional Chinese Herb Medicine (TCHM), which has been applied to treat cold, dry cough, toothaches, rheumatism, hypertension and so on. In addition, it has been used widely as spices since its highly aromas. The aim of this review is to compile and update the current progresses of ethnomedicinal uses, phytochemistry, pharmacology and toxicology of . All the data on were based on different classical literary works, multiple electronic databases including SciFinder, Web of Science, PubMed, etc. The results showed that ninety-seven compounds have been identified from rhizome of , including terpenoids, phenolics, cyclic dipeptides, flavonoids, diarylheptanoids, fatty acids and esters. Modern pharmacology studies revealed that extracts or secondary metabolites of the herb possessed anti-inflammatory, anti-oxidant, anti-tumorous, anti-bacterial, and anti-angiogenesis effects, which were closely related to its abundant ethnomedicinal uses. In conclusion, although previous research works have provided various information of , more in-depth studies are still necessary to systemically evaluate phytochemistry, pharmacological activities, toxicity and quality control of this herb.
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http://dx.doi.org/10.3389/fphar.2021.675350 | DOI Listing |
Heliyon
January 2025
Laboratory of Molecular Toxicology, Faculty of Nature and Life Sciences, University of Jijel, 18000, Jijel, Algeria.
has been traditionally used in northeastern Algeria for treating gastrointestinal disorders, particularly ulcers. This study aimed to assess the gastroprotective, anti-inflammatory, and antioxidant properties of a crude hydroalcoholic extract derived from the leaves of , as well as its subsequent fractions. The gastroprotective effect was studied in an ethanol-induced ulcer model in mice.
View Article and Find Full Text PDFPlants (Basel)
January 2025
College of Agriculture and Environmental Science (CAES), University of South Africa, Priva Bag X06, Florida 0710, South Africa.
Plants have long been used to treat serious illnesses in both humans and animals. A significant underappreciated medicinal tree, Sond is utilized by many different ethnic groups to cure a wide range of illnesses. A variety of electronic databases, including ScienceDirect, Scopus, Scielo, Scifinder, PubMed, Web of Science, Medline, and Google Scholar, were used to search the literature on , using key words such as uses, survey, pharmacology, antigonococcal, toxicity, phytochemistry and others.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Pharmacology Unit, Biomedical Sciences Department, Faculty of Pharmacy, University of Alcalá, 28871 Alcalá de Henares, Spain.
The genus (Asteraceae) has been traditionally used in Mediterranean medicine for its anti-inflammatory, antioxidant, and antimicrobial properties. However, scientific research on this genus remains limited, highlighting the need for a comprehensive review of its chemical composition and pharmacological characteristics. This review compiles existing knowledge on species, focusing on their secondary metabolites, such as flavonoids, terpenes, and essential oils, as well as associated biological activities.
View Article and Find Full Text PDFNutrients
January 2025
Department of Pharmacology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 40-055 Katowice, Poland.
Background: It seems that some substances of plant origin may exert health-promoting activities in diabetes and its complications, including those concerning bones. Chrysin (5,7-dihydroxyflavone), present in honey, some plants, and food of plant origin, has been reported to exert, among others, antioxidative, anti-inflammatory and antidiabetic effects. The aim of this study was to investigate the effects of chrysin on the skeletal system of rats with experimental type 1 diabetes (T1D).
View Article and Find Full Text PDFMolecules
January 2025
Institute of Organic Chemistry with Center for Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Many biologically active compounds have been identified in the mucus of the garden snail , which are effective in the treatment of several diseases such as cancer, ulcers, wounds, etc. The incorporation of these compounds into the green synthesis of copper nanoparticles (CuONPs-Muc) was demonstrated in our previous study. Based on the synergistic effect of two reducing agents- snail mucus and ascorbic acid (AsA)-on CuSO.
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