Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1183/13993003.02610-2021 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The ABF4-bHLH28-COMT5 module regulates melatonin synthesis and root development for drought tolerance in citrus.
Plant J
March 2025
National Key Laboratory for Germplasm Innovation and Utilization of Horticultural Crops, College of Horticulture and Forestry Sciences, Huazhong Agricultural University, Wuhan, 430070, China.
Melatonin significantly influences the regulation of plant growth, development, and stress tolerance. However, the regulatory mechanisms underlying melatonin accumulation for drought tolerance in citrus are not fully understood. In this study, we first demonstrated that application of exogenous melatonin resulted in better drought tolerance by reducing water loss and maintaining redox homeostasis.
View Article and Find Full Text PDFBroad complex negatively regulates Fibrohexamerin/P25 by binding to the cis-element BMFA in the silkworm, Bombyx mori.
Int J Biol Macromol
March 2025
State Key Laboratory of Resource Insects, Southwest University, Chongqing 400715, China. Electronic address:
Silk proteins, as natural macromolecular substances, hold significant potential for applications in biomaterials and biomedical fields. The expression of silk protein genes exhibits spatiotemporal specificity. Broad Complex (BrC), a key primary response factor to 20-hydroxyecdysone, plays a crucial role in metamorphosis.
View Article and Find Full Text PDFA comprehensive review of neurotransmitter modulation via artificial intelligence: A new frontier in personalized neurobiochemistry.
Comput Biol Med
March 2025
Department of Basic Medical Sciences, Khoy University of Medical Sciences, Khoy, Iran. Electronic address:
The deployment of artificial intelligence (AI) is revolutionizing neuropharmacology and drug development, allowing the modulation of neurotransmitter systems at the personal level. This review focuses on the neuropharmacology and regulation of neurotransmitters using predictive modeling, closed-loop neuromodulation, and precision drug design. The fusion of AI with applications such as machine learning, deep-learning, and even computational modeling allows for the real-time tracking and enhancement of biological processes within the body.
View Article and Find Full Text PDFNanotechnology-leveraged CRISPR/Cas systems: icebreaking in trace cancer-related nucleic acids biosensing.
Mol Cancer
March 2025
State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology, Tianjin Key Laboratory of Industry Microbiology, International China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Ministry of Education, National and Local United Engineering Lab of Metabolic Control Fermentation Technology, Tianjin University of Science & Technology, Tianjin, 300457, China.
As promising noninvasive biomarkers, nucleic acids provide great potential to innovate cancer early detection methods and promote subsequent diagnosis to improve the survival rates of patient. Accurate, straightforward and sensitive detection of such nucleic acid-based cancer biomarkers in complex biological samples holds significant clinical importance. However, the low abundance creates huge challenges for their routine detection.
View Article and Find Full Text PDFProgrammable solid-state condensates for spatiotemporal control of mammalian gene expression.
Nat Chem Biol
March 2025
Center of Synthetic Biology and Integrated Bioengineering, School of Engineering, Westlake University, Hangzhou, China.
Engineering of nuclear condensates with chemically inducible gene switches is highly desired but challenging for precise and on-demand regulation of mammalian gene expression. Here, we harness the phase-separation capability of biomolecular condensates and describe a versatile strategy to chemically program ligand-dependent gene expression at various stages of interest. By engineering synthetic anchor proteins capable of tethering various genetically encoded condensate structures toward different cellular compartments or gene products of interest, inducible regulation of transcriptional and translational activities was achieved at different endogenous and episomal loci using the same sets of anchor proteins and synthetic solid-state condensates.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!