AI Article Synopsis
- * Symptoms included recurrent venous thromboembolism, persistent hypokalemia, and compression fractures in her lower back, raising concerns about ectopic hypercortisolism due to her age and rapid disease progression.
- * Ultimately, tests identified a pituitary microadenoma as the source of excess cortisol, emphasizing that CD can cause acute health issues and has a heightened risk of blood clots linked to elevated cortisol levels.
Article Abstract
Cushing's disease (CD) is the most common cause of endogenous cortisol excess. We discuss the case of a 60-year-old woman with recurrent venous thromboembolism, refractory hypokalemia, and lumbar vertebrae compression fractures with a rapidly progressive disease course. Ectopic hypercortisolism was suspected given the patient's age and rapid onset of disease. Investigations revealed cortisol excess from a pituitary microadenoma. This case demonstrates that CD can present with severe findings and highlights the increased risk of venous thromboembolism in hypercortisolism, especially in CD.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545141 | PMC |
| http://dx.doi.org/10.1080/08998280.2021.1953950 | DOI Listing |
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