Electro-physiological sensing devices are becoming increasingly common in diverse applications. However, designing such sensors in compact form factors and for high-quality signal acquisition is a challenging task even for experts, is typically done using heuristics, and requires extensive training. Our work proposes a computational approach for designing multi-modal electro-physiological sensors. By employing an optimization-based approach alongside an integrated predictive model for multiple modalities, compact sensors can be created which offer an optimal trade-off between high signal quality and small device size. The task is assisted by a graphical tool that allows to easily specify design preferences and to visually analyze the generated designs in real-time, enabling designer-in-the-loop optimization. Experimental results show high quantitative agreement between the prediction of the optimizer and experimentally collected physiological data. They demonstrate that generated designs can achieve an optimal balance between the size of the sensor and its signal acquisition capability, outperforming expert generated solutions.
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http://dx.doi.org/10.1038/s41467-021-26442-1 | DOI Listing |
Sensors (Basel)
December 2024
Biofluids Laboratory, Perm National Research Polytechnic University, 614990 Perm, Russia.
Simulating the cardiac valves is one of the most complex tasks in cardiovascular modeling. As fluid-structure interaction simulations are highly computationally demanding, machine-learning techniques can be considered a good alternative. Nevertheless, it is necessary to design many aortic valve geometries to generate a training set.
View Article and Find Full Text PDFBiomimetics (Basel)
October 2024
CYBRES GmbH, Research Center of Advanced Robotics and Environmental Science, Melunerstr. 40, 70569 Stuttgart, Germany.
This work focuses on biohybrid systems-plants with biosensors and actuating mechanisms that enhance the ability of biological organisms to control environmental parameters, to optimize growth conditions or to cope with stress factors. Biofeedback-based phytoactuation represents the next step of development in hydroponics, vertical farming and controlled-environment agriculture. The sensing part of the discussed approach uses (electro)physiological sensors.
View Article and Find Full Text PDFIEEE Trans Neural Syst Rehabil Eng
January 2023
Recent developments in brain-machine inter-face technology have rendered seizure prediction possible. However, the transmission of a large volume of electro-physiological signals between sensors and processing apparatuses and the related computation become two major bottlenecks for seizure prediction systems due to the constrained bandwidth and limited computational resources, especially for power-critical wearable and implantable medical devices. Although many data compression methods can be adopted to compress the signals to reduce communication bandwidth requirement, they require complex compression and reconstruction procedures before the signal can be used for seizure prediction.
View Article and Find Full Text PDFFront Bioeng Biotechnol
December 2021
State Key Laboratory of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of Display Material and Technology, School of Electronics and Information Technology, The First Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, China.
The electrophysiological signal can reflect the basic activity of cardiomyocytes, which is often used to study the working mechanism of heart. Intracellular recording is a powerful technique for studying transmembrane potential, proving a favorable strategy for electrophysiological research. To obtain high-quality and high-throughput intracellular electrical signals, an integrated electrical signal recording and electrical pulse regulating system based on nanopatterned microelectrode array (NPMEA) is developed in this work.
View Article and Find Full Text PDFNat Commun
November 2021
Human Computer Interaction Lab, Saarland University, Saarland Informatics Campus, Saarbrücken, 66123, Germany.
Electro-physiological sensing devices are becoming increasingly common in diverse applications. However, designing such sensors in compact form factors and for high-quality signal acquisition is a challenging task even for experts, is typically done using heuristics, and requires extensive training. Our work proposes a computational approach for designing multi-modal electro-physiological sensors.
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