AI Article Synopsis
- Widespread human infections of SARS-CoV-2 raise concerns about reverse zoonosis, particularly in white-tailed deer due to their ability to contract the virus.
- Researchers conducted serosurveillance on 624 deer serum samples from four US states, focusing on both prepandemic and post-pandemic periods.
- The study found that 40% of samples taken in 2021 showed exposure to SARS-CoV-2, indicating that white-tailed deer populations have been significantly affected by the virus.
Article Abstract
Widespread human SARS-CoV-2 infections combined with human-wildlife interactions create the potential for reverse zoonosis from humans to wildlife. We targeted white-tailed deer () for serosurveillance based on evidence these deer have angiotensin-converting enzyme 2 receptors with high affinity for SARS-CoV-2, are permissive to infection, exhibit sustained viral shedding, can transmit to conspecifics, exhibit social behavior, and can be abundant near urban centers. We evaluated 624 prepandemic and postpandemic serum samples from wild deer from four US states for SARS-CoV-2 exposure. Antibodies were detected in 152 samples (40%) from 2021 using a surrogate virus neutralization test. A subset of samples tested with a SARS-CoV-2 virus neutralization test showed high concordance between tests. These data suggest white-tailed deer in the populations assessed have been exposed to SARS-CoV-2.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617405 | PMC |
| http://dx.doi.org/10.1073/pnas.2114828118 | DOI Listing |
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