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Comparison of whole genome sequencing typing tools for the typing of Belgian Legionella pneumophila outbreaks isolates.
Eur J Clin Microbiol Infect Dis
December 2024
Department of Microbiology and Infection Control, National Reference Centre for Legionella Pneumophila, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, 1090, Brussels, Belgium.
Whole genome sequencing (WGS) marks a turning point for outbreak investigations for microorganisms related to public health matters, like Legionella pneumophila (Lp). Here, we evaluated the available Lp WGS typing tools for isolates of previously documented Belgian outbreaks, as well as small groups of related and non-related isolates. One reference strain and 77 clinical and environmental isolates were evaluated.
View Article and Find Full Text PDFTargeting Key Risk Factors for Cardiovascular Disease in At-Risk Individuals: Developing a Digital, Personalized, and Real-Time Intervention to Facilitate Smoking Cessation and Physical Activity.
JMIR Cardio
December 2024
Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, Netherlands.
Health care is under pressure due to an aging population with an increasing prevalence of chronic diseases, including cardiovascular disease. Smoking and physical inactivity are 2 key preventable risk factors for cardiovascular disease. Yet, as with most health behaviors, they are difficult to change.
View Article and Find Full Text PDFBig data tax collection and management, enterprise financialization and enterprise innovation: Quasi-natural test evidence based on the "Golden Tax Phase III".
PLoS One
December 2024
School of Accounting, Lanzhou University of Finance and Economics, Lanzhou, People's Republic of China.
In the era of digital economy, big data tax collection and management has become an important governance tool for digital government. In this study, the quasi-natural test environment provided by the "Golden Tax Phase III" policy launched in 2013 and the method of propensity score matching and differentiation (PSM-DID) were used on combination of the samples of A-share listed enterprises in Shanghai and Shenzhen during 2010-2021 to analyze and demonstrate the impact of this policy on the innovation of the listed enterprises. To ensure the robustness of these findings, various statistical techniques such as parallel trend tests, placebo tests, and the explained variable replacement were employed.
View Article and Find Full Text PDFIncidence and Risk of Cardiovascular Outcomes in Patients With Anorexia Nervosa.
JAMA Netw Open
December 2024
Health Data Analytics and Statistics Center, Office of Data Science, Taipei Medical University, New Taipei City, Taiwan.
Importance: Anorexia nervosa (AN) is commonly associated with cardiovascular complications.
Objective: To investigate the trajectories of the risk of cardiovascular conditions in a nationwide cohort of patients with AN in Taiwan.
Design, Setting, And Participants: From a population-based health insurance database from January 1, 2011, to December 31, 2021, this longitudinal cohort study identified patients with AN and controls through propensity score matching at a 1:10 ratio according to sex, age, urbanization level of residence, socioeconomic status, and year of diagnosis.
Metformin lowers risk of hearing loss and mortality in type 2 diabetes.
Diabetes Obes Metab
December 2024
Department of Otorhinolaryngology, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital, Yilan, Taiwan.
Aims: To assess the association between metformin use and the risk of sudden sensorineural hearing loss (SSNHL) in patients with Type 2 diabetes (T2D), a population at elevated risk for SSNHL.
Materials And Methods: This cohort study utilized data from Taiwan's National Health Insurance Research Database, following T2D patients from 2008 to 202 database's baseline. Metformin use was defined as achieving ≥80% of the medication possession ratio (MPR) and ≥28 cumulative defined daily doses (cDDD) within three months.
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