Rationale: Total hip arthroplasty (THA) with a polyethylene (PE) liner is 1 of the most effective and successful treatment strategies for end-stage hip disorders. Vitamin E-infused highly cross-linked polyethylene is theoretically known to prevent failure due to oxidative degradation in the body, and is resistant to wear; therefore, successful long-term survival of THA is expected.
Patient Concerns: In June 2019, approximately 1.5 years after THA, the patient sat down and stood up without any specific issue; however, an unusual bullet sound occurred around the left hip joint. Since then, his discomfort persisted, and he was admitted to the emergency department.
Diagnosis: Plain radiography and metal artifact reduction computed tomography performed in the emergency department revealed eccentric elevation of the prosthetic femoral head and suspected PE liner failure.
Intervention: Revision surgery was performed for modular component exchange. To reduce the dislocation risk without performing cup exchange, conversion to dual-mobility articulation was performed.
Outcomes: During the regular follow-up post-surgery, the patient could perform daily life activities without any discomfort, and dislocation was not observed. At 2 years postoperatively, no significant changes were observed in the radiographic images.
Lessons: This case report presents an unexpected failure of THA due to superior rim fracture and excessive wear at the locking mechanism of the vitamin E-infused highly cross-linked polyethylene liner. This is an interesting case, as early PE liner failure occurred without strong labor intensity or trauma. A modular component exchange was performed with a dual-mobility bearing, and no issues were observed approximately 2 years after the reoperation. Therefore, third-generation highly cross-linked polyethylene liners can also cause early failure without a clear cause, and this case report highlights the necessity of considering several strategies for reoperation.
Study Design: Case report.
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http://dx.doi.org/10.1097/MD.0000000000027454 | DOI Listing |
Langmuir
March 2025
Engineering Research Center for Biomedical Materials, Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, Hefei 230601, China.
The development of antibacterial sponges with both high water-absorbing and mechanical properties is highly desirable for attaining efficient hemostasis and closure of noncompressible wounds, but remains challenging. General methods, such as increasing porosity, to improve the water absorption of sponges inevitably compromise their mechanical properties. Herein, a chitin (CT)/quaternized chitosan (QCS) sponge with the desirable properties was fabricated by freeze-drying the chemically and physically dual cross-linked CT/QCS hydrogel with enhanced hydrophilicity.
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March 2025
Department of Perioperative Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Background autofluorescence is enhanced in human tissue relative to small animals and presents a barrier to fully realizing the potential of novel multiplex methods in human studies. In particular, lipofuscin (LF) is an interfering pigment in multiplex fluorescence assays. Lipofuscin (LF) is a highly cross-linked aggregate of oxidized lipids, proteins, sugars, and metal ions that accumulates in lysosomes with age, and is strongly fluorescent across wavelengths that interfere with signals from common fluorophores.
View Article and Find Full Text PDFNat Commun
March 2025
Suzhou Laboratory, Suzhou, Jiangsu, China.
Multimodal optical-materials are highly desirable due to their advantages in enhancing information security, though independent modulation is challenging, especially accurately controlling the orthogonal relationship between the structural coloration (SC) and fluorescence (FL) pattern. Herein, we report a strategy which combines programmable structural coloration and switchable circularly polarized luminescence (CPL) for multimodal information encryption. Using photomask with aligned grating, programmable periodic patterns are fabricated on a polydiacetylene (PDA) gel film, which produces image in tunable structural colors.
View Article and Find Full Text PDFJ Immunol Methods
March 2025
Department of Plant Biotechnology, School of Biotechnology, Madurai Kamaraj University, Madurai, India.
An electrochemical CCLP-AuNPs (Calcium Cross Linked Pectin with Gold nanoparticles)-based biosensor was developed for sensitive detection and discrimination of carcinoembryonic antigen (CEA) based on dual signal amplification of gold nanoparticles tagged enzymatic catalysis. The electrochemical biosensor was fabricated by assembly of CCLP-AuNp modified GCE and subsequently anti CEA was immobilized on the modified GCE followed by the addition of CEA protein and then forming a sandwich-type conjugate was formed when the biosensor was successively reacted with Au-Anti CEA-HRP(Gold nanoparticles tagged with the antibody Carcinoembryonic antigen labelled with Horse radish peroxidase). In the presence of hydroquinone and hydrogen peroxide, in the PB(phosphate buffer) solution resulted in the fabrication of biosensor.
View Article and Find Full Text PDFFood Chem
February 2025
Department of Food and Engineering, Jinan University, Guangzhou 510632, China; Guangdong-Hong Kong Joint Innovation Platform for the Safety of Bakery Products, Guangzhou 510632, China. Electronic address:
As a natural pigment, anthocyanins show different colours in a wide pH range and can be used to prepare pH-responsive smart packaging films. However, free anthocyanins have obvious disadvantages, including easy degradation under light and easy migration into foods. This study used acrolein (ACR), a highly reactive β-unsaturated aldehyde, to cross-link anthocyanin and chitosan (CS).
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