AI Article Synopsis
- A phytochemical study of the Ba-wang-bian traditional Chinese medicine led to the isolation of 11 diterpenoids and two triterpenoids.
- New compounds identified included ingenane and ingol diterpenoids, determined through various spectroscopic techniques.
- The new compounds showed moderate cytotoxic effects on human lung cancer cells (A549), with IC values of 14.84 and 27.11 µM, indicating potential anti-cancer properties.
Article Abstract
Phytochemical investigation on the 95% EtOH extract of the Traditional Chinese Medicine (TCM) (Ba-wang-bian in Chinese) led to the isolation of 11 diterpenoids (-) and two triterpenoids ( and ). Among them, compounds and were new ingenane and ingol diterpenoids, respectively. Their structures were elucidated by a combination of spectroscopic analyses (1 D and 2 D NMR, HRMS, ECD, UV, and IR data) and chemical methods. Compounds and exhibited moderate cytotoxicities against human lung cancer cell line A549 with IC values of 14.84 ± 0.56 and 27.11 ± 1.65 µM, respectively.
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| http://dx.doi.org/10.1080/14786419.2021.1993215 | DOI Listing |
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