Bone fracture healing within a continuum bone remodelling framework.

Comput Methods Biomech Biomed Engin

Institute of Applied Mechanics, University of Erlangen-Nuremberg, Erlangen, Germany.

Published: July 2022

Bone fracture healing is a complex process which is still under research. Computer-aided patient-specific prediction of bone development, fracture risk, prevention and treatment approaches promises a significant milestone in clinical practice. With this long-term goal in mind, a novel model is presented and examined in this work in the context of continuum bone remodelling. Therein, a clear distinction is made between external mechanical stimulation and the biological healing process of an injured bone tissue. The model is implemented within a finite element framework and investigated for the example of a fractured proximal femur head. The results show promising perspectives for further application. Besides, the model offers the possibility of easily integrating other factors like age-dependency and the availability of nutrition. For the future, further studies with large clinical datasets are essential for validation.

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Source
http://dx.doi.org/10.1080/10255842.2021.1998465DOI Listing

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