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Chem Senses
January 2025
Department of Biological Science, Florida State University, Tallahassee, FL, United States.
Although animals can reliably locate and recognize odorants embedded in complex environments, the neural circuits for accomplishing these tasks remain incompletely understood. Adaptation is likely to be important as it could allow neurons in a brain area to adjust to the broader sensory environment. Adaptive processes must be flexible enough to allow the brain to make dynamic adjustments, while maintaining sufficient stability so that organisms do not forget important olfactory associations.
View Article and Find Full Text PDFPLoS One
December 2024
Machine Learning Group, Centrum Wiskunde & Informatica, Amsterdam, The Netherlands.
The acquisition of knowledge and skills does not occur in isolation but learning experiences amalgamate within and across domains. The process through which learning can accelerate over time is referred to as learning-to-learn or meta-learning. While meta-learning can be implemented in recurrent neural networks, these networks tend to be trained with architectures that are not easily interpretable or mappable to the brain and with learning rules that are biologically implausible.
View Article and Find Full Text PDFJ Ethnopharmacol
January 2025
Central Laboratory, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address:
Ethnopharmacological Relevance: Epimedium Tourn. ex L. is a traditional Chinese medicine used for thousands of years in China to treat forgetfulness.
View Article and Find Full Text PDFBMC Ecol Evol
December 2024
Department of Biomedical Sciences, University of Edinburgh, Edinburgh, UK.
Background: Citizen Science (CS) offers a promising approach to enhance data collection and engage communities in conservation efforts. This study evaluates the use of CS in environmental DNA (eDNA) monitoring for Mediterranean monk seal conservation. We validated CS by assessing the effectiveness of a newly developed CS-friendly filtration system called "WET" (Water eDNA Trap) in eDNA detection, addressing technical challenges, and analysing volunteer faults.
View Article and Find Full Text PDFMol Neurobiol
December 2024
Guangxi Key Laboratory of Brain and Cognitive Neuroscience, Faculty of Basic Medical Sciences, Guilin Medical University, Guilin, 541199, Guangxi, China.
The neural mechanisms underlying the natural and maladaptive forgetting of established memory remain largely unknown. Brain disease states might hijack the physiological forgetting mechanisms, resulting in maladaptive forgetting such as accelerated forgetting that contributes to cognitive decline in various neurologic conditions including epilepsy. Based on the key role of the integrated stress response (ISR) in memory storage and maintenance, we determined whether the ISR underpins natural and accelerated forgetting.
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