Purpose: To compare the dosimetric differences between intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in the treatment of male and female thymoma.
Material And Methods: This single-institutional analysis included 20 patients with thymoma treated with RT between January 2017 and December 2020. Twenty patients were retrospectively planned for IMRT (IMRT1 with an average field angle of 216°, 288°, 0°, 72°,and 144°; IMRT2 with fan-shaped field angles of 280°, 320°, 0°, 40°, and 80°) and VMAT (VMAT1 with two arcs ranging form 280° to 80°,clockwise and then counterclockwise; VMAT2 with two 360° arcs). The plans for all investigated RT modalities were optimized for a prescriptional dose of 50Gy and fractional dose of 2.0Gy. Planning target volume (PTV) and organs-at-risk (OARs: heart, breasts, lungs, spinal cord, and esophagus) dosimetric parameters were compared.
Results: All plans met the preparation aims for all the included metrics. There was little difference in the median values of PTV parameters (D, D, D, homogeneity index[HI], and conformity index [CI]). The CI of the VMAT2 plan was the closest to 1 in both therapy groups. The monitor unit (MU) of IMRT2 and the estimated total delivery time of VMAT1 were the lowest in both therapy groups and were statistically significant. In the male group, the lung parameters (D, V, V, and V) for VMAT1 were the lowest and showed statistical significance. In the female group, the lung parameters (D, V, V, and V) and bilateral breast parameters (Dmean, V, V, and V) of IMRT2 were the lowest and showed statistical significance.
Conclusions: In male thymoma patients undergoing postoperative RT (PORT) treatment, the choice of fan-shaped VMAT may be a better option for protecting the lungs. For female thymoma patients receiving PORT, fan-shaped IMRT can better protect the lungs and breasts. The fan-shaped field performed better than the average and the full arc fields in PORT for thymoma.
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http://dx.doi.org/10.1016/j.canrad.2021.07.037 | DOI Listing |
J Fungi (Basel)
November 2024
Institute of Crop Science and Resource Conservation-Plant Pathology, Rheinische Friedrich-Wilhelms-Universitaet Bonn, 53115 Bonn, Germany.
Microscopic evidence demonstrated a strictly biotrophic lifestyle of the scab fungus on growing apple leaves and characterised its hemibiotrophy as the combination of biotrophy and saprotrophy not described before. The pathogen-host interface was characterised by the formation of knob-like structures of the fungal stroma appressed to epidermal cells as early as 1 day after host penetration, very thin fan-shaped cells covering large parts of the host cell lumen, and enzymatic cuticle penetration from the subcuticular space limited to the protruding conidiophores. The cell wall had numerous orifices, facilitating intimate contact with the host tissue.
View Article and Find Full Text PDFMater Horiz
January 2025
Stealth & Camouflage Division, Defence Material Store R & D Establishment, DRDO, Kanpur, UP 208013, India.
A high-performance stealth platform is one of the crucial requirements in defence technology that could practically be realized by building effective microwave frequency selective surface (FSS) absorbers. Herein, we report the design and manufacturing of an absorber by tuning the rheology of cell architecture. Initially, a fan-shaped cell (10.
View Article and Find Full Text PDFMaterials (Basel)
September 2024
Key Laboratory of Micro-Nano Sensing and IoT of Wenzhou, Wenzhou Institute of Hangzhou Dianzi University, Wenzhou 325038, China.
A dual fan-shaped structure covered with Ag films was investigated for generating twin photonic hooks (t-PHs). The t-PH characteristics of this structure are studied using the Finite-Difference Time-Domain (FDTD) method. The results show that by designing appropriate fan-shaped opening angles and angles of Ag films coverage, the switching between t-PHs, S-shaped t-PHs, and W-shaped t-PHs can be achieved, along with controlling over the bending angles.
View Article and Find Full Text PDFCurr Biol
November 2024
Neural Diversity Lab, Department of Biology, University of New Mexico, 219 Yale Blvd Ne, Albuquerque, NM 87131, USA. Electronic address:
Complex behaviors arise from neural circuits that assemble from diverse cell types. Sleep is a conserved behavior essential for survival, yet little is known about how the nervous system generates neuron types of a sleep-wake circuit. Here, we focus on the specification of Drosophila 23E10-labeled dorsal fan-shaped body (dFB) long-field tangential input neurons that project to the dorsal layers of the fan-shaped body neuropil in the central complex.
View Article and Find Full Text PDFBiosensors (Basel)
August 2024
Key Laboratory of Biorheological Science and Technology, Ministry of Education and Bioengineering College, Chongqing University, Chongqing 400044, China.
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