Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1542/pir.2020-002279 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
High circulation of pertussis in infants and close contacts in Antananarivo, the capital of Madagascar in Africa, and Cambodia in Asia.
BMC Infect Dis
February 2025
Center for Translational Science, Institut Pasteur, Paris cité University, Paris, France.
Background: Reliable data on whooping cough, a highly contagious disease sometimes fatal for infants, are largely lacking in low- and middle-income countries.
Methods: We conducted a hospital-based prospective study (PS) on infants, and a household contact-case investigation (CCI) for positive cases throughout Cambodia and in the city of Antananarivo, Madagascar, between 2017 and 2019. The PS, in which Bordetella diagnostics (qPCR) were performed, included infants aged ≤6 months presenting with ≥5 days of cough associated with one pertussis-like symptom.
Intrafamilial neurological phenotypic variability due to either biallelic or monoallelic pathogenic variants in .
Front Neurol
October 2024
Department of Pediatrics, Pediatric Neurology, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
Article Synopsis
- The study focuses on three siblings with severe early-onset neurological issues linked to compound heterozygous variants in a specific gene, highlighting symptoms like muscular hypotonia, seizures, and apnoea.
- Two of the siblings died young, with suspected causes related to their conditions, while the third sibling developed epilepsy and mild intellectual impairment.
- Genetic testing revealed both maternal and paternal pathogenic variants associated with the severe phenotype of developmental epileptic encephalopathy (DEE), emphasizing the need for further research to understand unusual clinical cases related to these genetic disorders.
An Unusual Cause of Increasing Excessive Daytime Sleepiness in a CPAP-treated Obstructive Sleep Apnea Patient.
Sleep Sci
June 2024
Department of Pneumology, Centre Hospitalier Universitaire (CHU) Saint-Pierre, Brussels, Belgium.
The onset of narcolepsy type 1 (NT1) occurs after 50 years of age in less than 2% of the cases. In older adults, the diagnosis is often delayed due to the presence of neurological degenerative and inflammatory comorbidities and overlapping sleep disorders. We report the case of a 63-year-old man with a 5-year history of excessive daytime sleepiness (EDS) and a 2-year diagnosis of obstructive sleep apnea syndrome (OSAS), which.
View Article and Find Full Text PDFCharacteristics of non-sleep related apneas in children with alternating hemiplegia of childhood.
Eur J Paediatr Neurol
January 2024
Department of Pediatrics, Division of Neurology and Developmental Pediatrics, Duke University School of Medicine, Durham, NC, United States. Electronic address:
Background: Non-sleep related apnea (NSA) has been observed in alternating hemiplegia of childhood (AHC) but has yet to be characterized.
Goals: Investigate the following hypotheses: 1) AHC patients manifest NSA that is often severe. 2) NSA is usually triggered by precipitating events.
Obstructive sleep apnea and epilepsy: understanding the pathophysiology of the comorbidity.
Int J Physiol Pathophysiol Pharmacol
August 2023
Department of Physiology, Chirayu Medical College & Hospital Bhopal, Madhya Pradesh, India.
Obstructive sleep apnea (OSA) is a sleep disorder of significant health concern with a high prevalence in the general population. It has been found to exhibit a high incidence of comorbidity with epilepsy, the exact underlying pathophysiology of which still remains poorly understood. OSA is characterized by apnea/hypopnea spells and arousals, leading to intermittent hypoxemia and sleep deprivation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!