A novel calix[]triazolium was synthesized and exhibited excellent selectivity for AMP. The binding between calix[]triazolium and chromenolate anions forms a non-fluorescent complex and the resulting supramolecular ensemble selectively detects AMP in water and induces "turn-on" fluorescence. The sensing platform is the first macrocyclic system to discriminate AMP from ADP and ATP through fluorescence changes.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1039/d1cc04950j | DOI Listing |
RSC Adv
November 2022
College of Pharmacy, Seoul National University 1 Gwanak-ro, Gwanak-gu Seoul 08826 Korea
Since adenosine monophosphate (AMP) is closely related to many diseases, the measurement of AMP is important for the diagnosis and treatment of related diseases. Among the AMP sensors reported thus far, sensors that selectively recognize AMP, not ADP or ATP, are rare, and complex experimental procedures and additional instruments are required for AMP recognition. We developed a colorimetric chemosensor using calix[6]triazolium (CT6) and intended to use it for the simple and rapid detection of AMP.
View Article and Find Full Text PDFChem Commun (Camb)
November 2021
College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.
Chemistry
October 2014
Department of Chemistry, Indian Institute of Technology, Powai, Mumbai-400076 (India), Fax: (+91) 22-2576-7152.
A triazolium-anthracenyl calix[4]arene conjugate (L) was synthesized by methylating the precursor triazole derivative and then characterized. The potential of the cationic L to differentiate nucleoside triphosphates (NTPs) from their mono- and diphosphates was demonstrated. Due to its unique combination of arms with the calix-platform, a fluorescence enhancement was observed for L with all the NTPs, whereas there is no report with such enhancement being exhibited in case of all the NTPs.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!