AI Article Synopsis
- Mitochondria in cells, particularly in skeletal muscle, show a variety of forms and functions, indicating their heterogeneity.
- Researchers have identified distinct groups of mitochondria in skeletal muscle but are still trying to understand how these differences help maintain energy balance during muscle activity.
- Advancements in imaging technologies are opening new research paths to explore the specific roles of these diverse mitochondrial subpopulations in muscle cells.
Article Abstract
Across different cell types and within single cells, mitochondria are heterogeneous in form and function. In skeletal muscle cells, morphologically and functionally distinct subpopulations of mitochondria have been identified, but the mechanisms by which the subcellular specialization of mitochondria contributes to energy homeostasis in working muscles remains unclear. Here, we discuss the current data regarding mitochondrial heterogeneity in skeletal muscle cells and highlight potential new lines of inquiry that have emerged due to advancements in cellular imaging technologies.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554132 | PMC |
| http://dx.doi.org/10.3389/fcell.2021.757305 | DOI Listing |
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