AI Article Synopsis
- A 72-year-old woman with acute myeloid leukemia (AML) developed involuntary movements following an HHV-6 viral infection after a stem cell transplant.
- Neurologic examination revealed choreoathetotic movements, characterized by irregular and writhing motions not typically seen in other disorders.
- This case is the first documented instance of adult-onset chorea linked to HHV-6, raising questions about whether the movements were directly caused by the virus or by an autoimmune response triggered by the infection.
Article Abstract
Background: Human herpesvirus-6 (HHV-6) has been associated with various neurologic disorders, but movement disorders are rare. This case describes a patient who developed a choreoathetotic movement disorder in the setting of HHV-6 infection.
Case Report: A 72-year-old woman with AML and recent HHV-6 encephalitis following stem cell transplant presented with involuntary movements. Neurologic examination demonstrated motor impersistence and irregular non-stereotyped writhing movements consistent with a choreoathetotic movement disorder secondary to HHV-6 infection.
Discussion: This is the first literature reported case of adult-onset chorea associated with HHV-6 infection, though it remains unclear if the movement disorder was from the infection or a secondary autoimmune response.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533650 | PMC |
| http://dx.doi.org/10.5334/tohm.657 | DOI Listing |
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