One of the most commonly used models in survival analysis is the additive Weibull model and its generalizations. They are well suited for modeling bathtub-shaped hazard rates that are a natural form of the hazard rate. Although they have some advantages, the maximum likelihood and the least square estimators are biased and have poor performance when the data set contains a large number of parameters. As an alternative, the expectation-maximization (EM) algorithm was applied to estimate the parameters of the additive Weibull model. The accuracy of the parameter estimates and the simulation study confirmed the advantages of the EM algorithm.
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http://dx.doi.org/10.1155/2021/1179856 | DOI Listing |
Materials (Basel)
January 2025
Department of Mechanical Engineering, Kunsan National University, Gunsan-si 54150, Republic of Korea.
The key structural components of a wind turbine blade, such as the skin, spar cap, and shear web, are fabricated from fiber-reinforced composite materials. The spar, predominantly manufactured via resin infusion-a process of resin injection and curing in carbon fibers-is prone to initial defects, such as pores, wrinkles, and delamination. This study suggests employing the pultrusion technique for spar production to consistently obtain a uniform cross-section and augment the reliability of both the manufacturing process and the design.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Brodalumab, a humanized monoclonal antibody that targets the interleukin-17 receptor A, is primarily used to manage moderate-to-severe plaque psoriasis. Although it has demonstrated favorable efficacy and safety in clinical trials, the strict inclusion and exclusion criteria may not fully reflect its safety profile in real-world settings. As its use becomes more widespread in clinical practice, understanding its safety in real-world applications is crucial.
View Article and Find Full Text PDFJ Prosthodont
January 2025
Department of Dentistry, Federal University of Rio Grande do Norte (UFRN), Lagoa Nova, Natal, Brazil.
Purpose: To assess the impact of staining and multiple firings on the mechanical, optical, and surface characteristics of zirconia-containing lithium silicate ceramics (ZLS).
Materials And Methods: Ninety ZLS discs (Suprinity, VITA Zahnfabrick) were divided according to the "Number of firings" protocol: Ctr-control, no characterization; SC-single firing cycle (for characterization, crystallization and staining simultaneously); and DC-double firing cycle (crystallization firing cycle was performed separately from the staining firing). Extrinsic pigmentation was performed to replicate the characterization of a monolithic restoration.
J Biomed Mater Res B Appl Biomater
January 2025
Dental Materials Unit, Center for Dental Medicine, Clinic for Masticatory Disorders and Dental Biomaterials, University of Zurich, Zurich, Switzerland.
The purpose of this study was to evaluate the characteristics of the ceramic bonding to cobalt-chromium (Co-Cr) alloys fabricated by casting, milling, and additive manufacturing, compared with zirconia and nickel-chromium. One hundred specimens (N = 100), prepared with the dimensions of 25 × 3 × 0.5 mm, were assigned to five groups (n = 20): presintered milled Co-Cr (Group M), additively manufactured Co-Cr (Group SLM), cast Co-Cr (Group C), presintered zirconia (Group Zi), and cast Ni-Cr (Group Ni).
View Article and Find Full Text PDFAccid Anal Prev
March 2025
Department of Civil Engineering, Indian Institute of Technology Roorkee, Roorkee, 247667, India. Electronic address:
Pedestrians use visual cues (i.e., gaze) to communicate with the other road users, and visual attention towards the surrounding environment is essential to be situationally aware and avoid oncoming conflicts.
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