Unlabelled: We conducted a cross-sectional study to compare the impact of social distancing and lifestyle changes that occurred during Corona Virus Disease 2019 (COVID-19) lockdown on children and adolescents with and without Neurodevelopmental Disorders (NDDs). An online questionnaire was administered in order to investigate the effects of NDD condition, socio-demographic status, familiar/home environment and COVID-19 exposure on their lives during a two months period of social isolation. We used logistic regression, focusing on five endpoints (remote learning, lifestyle, stress/anxiety, sociality, scolding) to define the extent of these effects. Most questions were paired up to parents and children, to verify the occurrence of agreement. 8305 questionnaires were analyzed, 1362 of which completed by NDDs and 6943 by controls. Results showed that the presence of a NDD, compared to controls, had a significant impact on: (i.e. subjects with NDDs experienced more difficulties in attending online classes and studying), (i.e. subjects with NDDs missed their schoolmates less), S (i.e. subjects with NDDs were scolded more often) and (i.e. subjects with NDDs were perceived by their parents as more anxious). Substantial agreement between parents and children arose from questions concerning , and . The current study actually points out that having a NDD gives account for a stronger influence on school performance and on behavioral and psychological aspects, during a two months lockdown. Such results may provide useful information to governments and school authorities on how carrying through supportive strategies for youth affected by NDDs.
Supplementary Information: The online version contains supplementary material available at 10.1007/s12144-021-02321-2.
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http://dx.doi.org/10.1007/s12144-021-02321-2 | DOI Listing |
Curr Neurol Neurosci Rep
December 2024
Kennedy Krieger Institute and Department of Psychiatry & Behavioral Sciences-Child Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Purpose Of The Review: Preclinical and clinical evidence support the notion that neurodevelopmental disorders (NDDs) are synaptic disorders, characterized by excitatory-inhibitory imbalance. Despite this, NDD drug development programs targeting glutamate or gamma-aminobutyric acid (GABA) receptors have been largely unsuccessful. Nonetheless, recent drug trials in Rett syndrome (RTT), fragile X syndrome (FXS), and other NDDs targeting other mechanisms have met their endpoints.
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October 2024
Center for Alzheimer's and Related Dementias, National Institutes of Health, Bethesda, MD, 20892, USA.
Background: Alzheimer's disease and related dementias (ADRD) and Parkinson's disease (PD) are the most common neurodegenerative conditions. These central nervous system disorders impact both the structure and function of the brain and may lead to imaging changes that precede symptoms. Patients with ADRD or PD have long asymptomatic phases that exhibit significant heterogeneity.
View Article and Find Full Text PDFCureus
October 2024
Department of Physiotherapy, KLE (Karnataka Lingayat Education) College of Physiotherapy, Hubli, IND.
Introduction Neurodevelopmental disorders (NDDs) are responsible for childhood brain dysfunction and developmental disability. Physical therapists are important team members in providing a beneficial impact on the gross motor function of children with NDDs. Early intervention provides a beneficial effect on the improvement of gross motor function; however, most of the studies on treadmill training were in late age and the effect of early treadmill walking along with conventional physiotherapy was not studied.
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October 2024
Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain.
Child Psychiatry Hum Dev
October 2024
Department of Child and Adolescent Psychopathology, Amiens University Hospital, Amiens, France.
Individuals with neurodevelopmental disorders (NDDs) are more susceptible to developing severe or resistant mood disorders. However, they often face challenges in accessing specific treatments. To understand the barriers to treatment in this group, we conducted a secondary analysis of a multicenter observational study on 305 adolescents referred to specialized care (mean age 14.
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