We apply the technique of convex integration to obtain non-uniqueness and existence results for power-law fluids, in dimension . For the power index below the compactness threshold, i.e. , we show ill-posedness of Leray-Hopf solutions. For a wider class of indices we show ill-posedness of distributional (non-Leray-Hopf) solutions, extending the seminal paper of Buckmaster & Vicol [10]. In this wider class we also construct non-unique solutions for every datum in .
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http://dx.doi.org/10.1007/s00220-021-04231-7 | DOI Listing |
Clin Oral Investig
December 2024
Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, 510055, China.
Objectives: To compare the variations in the upper airway of children with skeletal Class II mandibular retrognathism treated with van Beek Headgear-Activator (vBHGA) and Twin-Block (TB) appliances.
Materials And Methods: 40 children were involved in this retrospective study and divided into two intervention groups: the vBHGA group and the TB group, each comprising 20 individuals with an average age of 11.13 years.
Front Psychol
December 2024
Ashridge Centre for Coaching, Hult International Business School, Berkhamsted, United Kingdom.
In this article we explore some of the processes involved in dealing with Social Difference (SD) in coaching. Using examples from our own practice, we consider several factors, including the identity work involved in navigating the experience of SD in one-to-one coaching. Dealing with experiences of difference, including social class, gender, race, ability, and sexuality can invoke complicated and powerful feelings.
View Article and Find Full Text PDFJ Am Chem Soc
December 2024
Department of Chemistry, New York University, New York, New York 10003, United States.
Complexity-generating reactions that access three-dimensional products from simple starting materials offer substantial value for drug discovery. While oxygen-containing heterocycles frequently feature unique, nonaromatic architectures such as spirocyclic rings, exploration of these chemical spaces is limited by conventional synthetic approaches. Herein, we report a copper-catalyzed annulation and alkene transposition cascade reaction that enables a modular preparation of complex, spirocyclic ethers from readily available alkenol substrates via a copper-catalyzed annulation and transannular 1,5-hydrogen atom transfer-mediated C-H functionalization.
View Article and Find Full Text PDFAnal Bioanal Chem
December 2024
Discovery Analytical Research, Merck & Co., Inc, 213 E Grand Ave, South San Francisco, CA, 94080, USA.
The site-specific antibody-drug conjugates (ADCs), particularly those utilizing the engineered cysteine in Fc fragments of mAbs (THIOMAB™ antibodies), have emerged as a novel class of biotherapeutics for cancer treatment. The engineered cysteine residues in these antibodies are capped by cysteine or glutathione through a disulfide bond. Prior to conjugation with linker-payloads, these caps need to be removed through a reduction process.
View Article and Find Full Text PDFJ Geom Anal
June 2024
Department of Mathematical Sciences, 1 University of Arkansas, SCEN 326, Fayetteville, AR 72701 USA.
CR functions on an embedded quadric always extend holomorphically to where is the closure of the convex hull of the image of the Levi form. When is a closed polygonal cone, we show that the Bergman kernel on the interior of is a derivative of the Szegö kernel. Moreover, we develop the Hardy space theory which turns out to be particularly robust.
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