Background: To study the psychosomatic options and dynamics in patients with eating disorders. To conduct a comparative study of psychosomatic characteristics of surveyed patients with eating disorders, taking into account the duration and severity of protein-energy deficiency and levels of catecholamines excretion; to reveal features of mental working capacity, basic mental processes and EEG data at different stages of eating disorders; to develop scientifically based effective methods and means for correcting pathological changes that have arisen as a result of prolonged protein-energy deficiency in eating disorders.
Methods: Catamnestic, statistical, clinico-psychopathological with somatic, psychological and laboratory examination, anthropometry, high-performance liquid chromatography, electroencephalography. Statistical analysis of collected data was processed using the program IBM SPSS Statistics 22, the confidence level p-value is ≤0.001.
Results: The long-term consequences of prolonged fasting in 500 women with eating disorders (ED), who applied for help at the RUDN department and were examined in 1987-2013, were studied. The most common somatic complications of prolonged protein-energy deficiency were investigated. In addition to the clinical method and anthropometry, to measure the efficiency of weight gain after prolonged alimentary deficiencies and to treat anorexia nervosa patients the pathopsychological method of "Shabalina's complex decoding" and analysis of catecholamine excretion rates in urine of patients with anorexia at different stages of therapy were used. Improvement of mental performance and general condition of the examined after applying the developed treatment was observed. Scientifically based principles of therapy, allowing to avoid complications of long-term fasting and during weight gain were suggested.
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JMIR Ment Health
January 2025
Division of Psychiatry, University College London, London, United Kingdom.
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December 2024
Azienda Ospedaliero Universitaria Pisana, Pisa, PI, Italy.
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Alzheimers Dement
December 2024
University of Pittsburgh, Pittsburgh, PA, USA.
Background: Recent studies have shown that patients with attention-deficit/hyperactivity disorder (ADHD) are more likely to be diagnosed with mild cognitive impairment (MCI) and Alzheimer's Disease (AD). Increased genetic risk for ADHD, measured with ADHD polygenic risk scores (ADHD-PRS), was associated with a more severe AD presentation, including worse cognitive function and higher tau pathology. Neuropsychiatric symptoms (NPSs) are common in AD and are hypothesized to occur with disease progression.
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January 2025
Department of Dermatology and Allergy, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
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View Article and Find Full Text PDFHealth Commun
January 2025
Department of Communication & Journalism, Texas A&M University.
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