Beyond the sacro-Iliac joints: Vertebral involvement in axial spondylarthritis.

Eur J Radiol

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

Published: November 2021

Imaging plays a central role in the diagnosis of axial spondylarthritis (axSpA). Commonly the sacroiliac joints are involved but vertebral involvement can occur in isolation in 1 out of 4 patients. Recognizing vertebral involvement patterns in axSpA can help establishing a diagnosis early and initiate therapy before irreversible changes have occurred. Magnetic resonance imaging (MRI) is considered the reference standard for early detection of inflammatory changes of the disease. Aims of this review are to present an overview of the imaging findings of vertebral involvement in axSpA, and to detail the current recommendations on the role of imaging in the diagnosis of axSpA in patients with isolated vertebral involvement.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejrad.2021.109982DOI Listing

Publication Analysis

Top Keywords

vertebral involvement
20
axial spondylarthritis
8
vertebral
5
involvement
5
sacro-iliac joints
4
joints vertebral
4
involvement axial
4
imaging
4
spondylarthritis imaging
4
imaging plays
4

Similar Publications

Case: We report a case of coccygeal dislocation complicated by defecatory dysfunction and discuss its treatment and mechanisms. A 58-year-old man was presented with coccygeal pain and defecatory dysfunction after sustaining an injury from a 1-m fall. Following diagnosis, a combined approach involving surgical treatment and physiotherapy was adopted, resulting in early symptom improvement and favorable long-term outcomes.

View Article and Find Full Text PDF

Variants in the SOX9 transactivation middle domain induce axial skeleton dysplasia and scoliosis.

Proc Natl Acad Sci U S A

January 2025

Department of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

SOX9 is a crucial transcriptional regulator of cartilage development and homeostasis. Dysregulation of is associated with a wide spectrum of skeletal disorders, including campomelic dysplasia, acampomelic campomelic dysplasia, and scoliosis. Yet how variants contribute to the spectrum of axial skeletal disorders is not well understood.

View Article and Find Full Text PDF

In this study, we explored the impact of different biomechanical loadings on lumbar spine motion segments, particularly concerning intervertebral disc degeneration (IVDD). We aimed to uncover the cellular milieu and mechanisms driving ossification in the nucleus pulposus (NP) during IVDD, a process whose underlying mechanisms have remained elusive. The study involved the examination of fresh NP tissue from the L3-S1 segment of five individuals, either with IVDD or healthy.

View Article and Find Full Text PDF

Inter-facility transfers to an urban level 1 trauma center and rates of secondary overtriage.

Eur J Trauma Emerg Surg

January 2025

Delray Medical Center, Division of Trauma and Critical Care Services, 5352 Linton Boulevard, Delray Beach, FL, 33484, USA.

Purpose: Many patients originally transported to non-trauma centers (NTC) require transfer to a trauma center (TC) for treatment. The aim was to analyze injury characteristics and outcomes of transfer patients and investigate the secondary overtriage (SOT).

Methods: Study included 2,056 transfers to an urban level 1 TC between 01/2016 and 06/2020.

View Article and Find Full Text PDF

A new 3D full-body scanner analyzing the sagittal and coronal balance of the adult spine: a preliminary prospective observational study.

Acta Neurochir (Wien)

January 2025

Department of Orthopaedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, 20 Boramae-Ro 5-Gil, Dongjak-Gu, Seoul, Republic of Korea.

Background: The degenerative spondylosis can cause the difficulty in maintaining sagittal and coronal alignment of spine, and X-ray parameters are the gold standard to analyze the malalignment. This study aimed to develop a new 3D full body scanner to analyze the spinal balance and compare it to X-ray parameters.

Methods: Ninety-seven adult participants who suffer degenerative spondylosis underwent 3D full body scanning, whole spine X-rays, clinical questionnaires and body composition analyses.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!