AI Article Synopsis
- Alzheimer's disease affects many people globally, and there's interest in using different types of exercise to help prevent or alleviate symptoms.
- Current research explored the effectiveness of concurrent exercise (a mix of running and strength exercises) on recognition memory deficits in a rat model simulating Alzheimer's disease.
- Findings revealed that while concurrent exercise did not help in preventing memory issues and increased oxidative stress in the brain, running alone was effective in preventing these recognition memory impairments.
Article Abstract
Alzheimer's disease affects thousands of people worldwide. Alternatives aiming to prevent the disease or reduce its symptoms include different physical exercise configurations. Here we investigate the potential of concurrent exercise to prevent recognition memory deficits in an Alzheimer's disease-like model induced by the hippocampal beta-amyloid (Aβ) injection in Wistar rats. We demonstrate that the concurrent exercise, which included running and strength exercises performed in the same exercise session, is ineffective in preventing recognition memory deficits in the Aβ rats. Besides, higher levels of reactive oxygen species were found in the concurrent exercise group's hippocampus. The running exercise administrated alone prevented recognition memory impairments.
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| http://dx.doi.org/10.1016/j.physbeh.2021.113631 | DOI Listing |
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