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Mortality Profile of Deaths Related to Infective Endocarditis in Brazil and Regions: A Population-Based Analysis of Death Records.
Trop Med Infect Dis
November 2024
Department of Specialized Medicine-Cardiology Discipline, School of Medicine and Surgery, Federal University of the State of Rio de Janeiro, Rua Silva Ramos, 32, Tijuca, Rio de Janeiro 20270-330, Brazil.
Background: Studies of infective endocarditis (IE) are generally limited to institutions, underlining the need for more comprehensive epidemiological research.
Objective: The aim of this study was to determine the mortality profile of IE-related deaths and related causes in Brazil at the national level and across regions.
Method: We conducted a population-based study using data from the country's mortality information system for the period 2000 to 2019.
The Fifth Annual Symposium of the Midwest Aging Consortium.
J Gerontol A Biol Sci Med Sci
December 2024
Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
As the healthcare burden caused by an increasingly aging population rapidly rises, a pressing need exists for innovative geroscience research that can elucidate aging mechanisms and precipitate the development of therapeutic interventions to support healthy aging. The Fifth Annual Midwest Aging Consortium Aging Research symposium, held from April 28-30, 2024, was hosted by The Ohio State University in Columbus, Ohio and featured presentations from investigators across the Midwestern United States. This report summarizes the research presented at the symposium, whose topics included cellular senescence and the aging brain, metabolism and metabolic interventions, nutrition, redox mechanisms and biomarkers, and stress mechanisms.
View Article and Find Full Text PDFHealth care concerns in women at midlife: differences by race, ethnicity, and neighborhood socioeconomic status.
Menopause
December 2024
Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Objectives: The aims of the study were to identify conditions diagnosed in at least 10% of midlife women living in the US upper midwest and to assess prevalence by age, race, ethnicity, and sociodemographic status.
Methods: The Rochester Epidemiology Project was used to conduct a cross-sectional prevalence study of 86,946 women between 40 and 59 years residing in a 27-county region of the United States on January 1, 2020. Diagnostic billing codes were extracted and grouped into broader condition categories using the Clinical Classification System Refined.
SAGES guidelines for the management of comorbidities relevant to metabolic and bariatric surgery.
Surg Endosc
January 2025
Department of Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Background: Patients who are under consideration for or have undergone metabolic and bariatric surgery frequently have comorbid medical conditions that may make their perioperative care more complex. These recommendations address routine intraoperative cholangiography in patients with bypass-type anatomy, the management of reflux disease after sleeve gastrectomy, and the optimal bariatric procedure for patients with comorbid inflammatory bowel disease.
Methods: A systematic review was conducted including studies published from 1990 to 2022 to address these questions.
The role of nutrition-related clinical trials in informing dietary recommendations for health and treatment of diseases.
J Clin Lipidol
October 2024
Midwest Biomedical Research, Addison, IL, United States; Indiana University School of Public Health, Bloomington, IN, United States.
Dietary guidance is based on a robust evidence base that includes high-quality clinical trials, of which some have been designed to establish causal relationships between dietary interventions and ASCVD risk reduction. However, the complexity associated with conducting these trials has resulted in criticism of nutrition and dietary recommendations because the strength and quality of evidence falls short of that for some pharmaceutical interventions. In this paper, we aim to promote greater awareness of the nutrition-related clinical trials that have been conducted showing ASCVD benefits and how this evidence has contributed to dietary recommendations.
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