Salomón Hakim (1922-2011) was a Colombian neurosurgeon and brain scientist This biography examines the social and cultural background through which he emerged as an inquisitive and multi-dimensional surgeon-scientist, and his lifelong contributions to the specialty of neurosurgery. With empirical knowledge in applied medical physics, electronics, electricity and chemistry, he understood the paradoxical phenomenon of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. This ultimately led Hakim to describe in exquisite detail the physics of the cranial cavity and brain hydrodynamics. His name is intertwined with the identification of the entity of a syndrome which had not previously been addressed in the medical literature: Normal Pressure Hydrocephalus (Hakim's syndrome). Additionally, he designed and built various models of valved shunting devices to treat the condition (eg the Hakim programmable valve). Through his selflessness and cogent work, Hakim left a legacy and intellectual heritage that has allowed many colleagues worldwide to save thousands of lives who would be otherwise condemned to oblivion.
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http://dx.doi.org/10.1177/09677720211054025 | DOI Listing |
Diagnostic delays prevent most Chagas disease patients from receiving timely therapy during the acute phase when treatment is effective. qPCR-based diagnostic methods provide high sensitivity during this phase but require specialized equipment and complex protocols. More simple and cost-effective tools are urgently needed to optimize early Chagas disease diagnosis in low-income endemic regions.
View Article and Find Full Text PDFInt J Nephrol Renovasc Dis
January 2025
Department of Pediatric, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
Background: Acute kidney injury (AKI) is common in critically ill children in the PICU, with incidence rates from 2.5% to 58%, impacting mortality and hospital duration. Early AKI detection is vital, but conventional hemodynamic monitoring often lacks specificity.
View Article and Find Full Text PDFArthritis Care Res (Hoboken)
January 2025
Monash University, Melbourne, Victoria, Australia.
Objective: This study aimed to identify the top 10 international research priorities for musculoskeletal health of people with generalized joint hypermobility.
Methods: A 3-round Delphi method utilizing an online survey was implemented. Three participant stakeholder groups were eligible for inclusion: (1) people with lived experience of joint hypermobility or their carers, (2) healthcare professionals, and (3) researchers with experience working with individuals with hypermobility.
World Neurosurg
January 2025
"Carol Davila" University of Medicine and Pharmacy, Bd. Eroii Sanitari 8, 050474, Bucharest, Romania; Central Military Emergency Hospital "Dr. Carol Davila", Neurosurgical Department, Street Calea Plevnei 134, 010825, Bucharest. Electronic address:
Microorganisms
December 2024
Institute of Horticulture, Lithuanian Research Centre for Agriculture and Forestry, Kaunas Str. 30, 54333 Babtai, Kaunas reg., Lithuania.
Plants inhabiting environments with suboptimal growth conditions often have a more pronounced capacity to attract and sustain microbial communities that improve nutrient absorption and expand abiotic stress tolerance. L. is a succulent plant of the family adapted to survive in sandy or rocky soils or dry tundra.
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