The current study investigated cognitive flexibility in preschool children with Autism Spectrum Disorder (ASD) and those with typical development using the Reverse Categorization (RC) task and the Dimensional Change Card Sort (DCCS) task. We further examined the relationship between non-verbal mental age (NVMA) and the performance on the two tasks. While no significant difference in performance on the RC task between the two groups was found, significantly more children in the typical developing group passed the DCCS task than children in the ASD group. NVMA was found to correlate with performance in both tasks in the typical developing group but not in the ASD group. When the children were matched on NVMA, no differences in task performance between the two groups were found. The current study found the disparity in performance in two groups on the RC and the DCCS tasks, hence illuminating the importance related to the selection of tasks when studying cognitive flexibility in preschool children with ASD. The study also cast some light on the involvement of NVMA in the performance on the RC and DCCS tasks.
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http://dx.doi.org/10.3389/fpsyg.2021.737631 | DOI Listing |
Sci Rep
December 2024
Brain Dynamics Lab, Interdisciplinary Center of Biomedical and Engineering Research for Health, Universidad de Valparaíso, Valparaíso, Chile.
Multi-state metastability in neuroimaging signals reflects the brain's flexibility to transition between network configurations in response to changing environments or tasks. We modeled these dynamics with a Kuramoto network of 90 nodes oscillating at an intrinsic frequency of 40 Hz, interconnected using human brain structural connectivity strengths and delays. We simulated this model for 30 min to generate multi-state metastability.
View Article and Find Full Text PDFClinics (Sao Paulo)
December 2024
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
Background: Hospitalization for Transurethral Prostate Resection (TURP) involves circadian rhythm disturbance - a possible cause of Postoperative Neurocognitive Disorder (POCD) in elderly patients. This study investigated whether melatonin ameliorated this effect.
Methods: A double-blind, randomized clinical trial used a battery of neuropsychological tests to evaluate cognitive performance of 118 patients aged ≥ 60, before TURP with spinal anesthesia, and at 21- and 180-days PO.
Geroscience
December 2024
Laboratory of Neurodegenerative Diseases, Center for Interdisciplinary Research and Innovation, Aristotle University of Thessaloniki (CIRI-AUTh), 54124, Thessaloniki, Greece.
The accurate diagnosis of aging-related neurocognitive disorders as early as possible, even in a phase that is characterized by the absence of clinical symptoms, is nowadays the holy grail of the neurosciences. R4Alz-R is a novel cognitive tool designed to objectively detect the subtle cognitive changes that emerge as the very first result of the aging processes and could be developed and broadened in a continuum from healthy aging to subjective cognitive impairment (SCI) and mild cognitive impairment (MCI), before reaching some type of dementia. The goal of the present study was to examine whether the R4Alz-R battery has the potential to detect these subtle changes.
View Article and Find Full Text PDFClin Pract
December 2024
Department of Experimental Medicine (Di.Me.S), University of Salento, 73100 Lecce, Italy.
Background/objectives: Osteoporosis causes a bone mass reduction and often determines acute and chronic pain. Understanding the biochemical and neurophysiological mechanisms behind this pain is crucial for developing new, effective rehabilitative and therapeutic approaches. This systematic review synthesizes recent advances in muscle-bone interactions and molecular pathways related to osteoporosis-associated pain.
View Article and Find Full Text PDFFront Psychol
December 2024
Department of Guidance and Psychological Counseling, Faculty of Education, Yildiz Technical University, Istanbul, Türkiye.
Objective: Metacognition, a multifaceted psychological construct, encompasses recognising and explaining one's cognitive processes and those of others. Notably, deficits in metacognitive abilities are linked with diminished social performance, reduced quality of life, and increased severity of Personality Disorders (PD). While there are other assessment tools available in Turkish for evaluating metacognition, none offer the same combination of speed, simplicity, flexibility, and multidimensionality for screening metacognitive abilities as the Metacognition Self-Assessment Scale (MSAS).
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