Objectives: To clarify real-world linguistic nuances around dying in hospital as well as inaccuracy in individual-level prognostication to support advance care planning and personalised discussions on limitation of life sustaining treatment (LST).
Design: Retrospective cross-sectional study of real-world clinical data.
Setting: Secondary care, urban and suburban teaching hospitals.
Participants: All inpatients in 12-month period from 1 October 2018 to 30 September 2019.
Methods: Using unsupervised natural language processing, word embedding in latent space was used to generate phrase clusters with most similar semantic embeddings to 'Ceiling of Treatment' and their prognostication value.
Results: Word embeddings with most similarity to 'Ceiling of Treatment' clustered around phrases describing end-of-life care, ceiling of care and LST discussions. The phrases have differing prognostic profile with the highest 7-day mortality in the phrases most explicitly referring to end of life-'Withdrawal of care' (56.7%), 'terminal care/end of life care' (57.5%) and 'un-survivable' (57.6%).
Conclusion: Vocabulary used at end-of-life discussions are diverse and has a range of associations to 7-day mortality. This highlights the importance of correct application of terminology during LST and end-of-life discussions.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557276 | PMC |
http://dx.doi.org/10.1136/bmjhci-2021-100464 | DOI Listing |
Sci Rep
December 2024
School of Public Administration, Guangzhou University, Guangzhou, 510006, China.
With the accelerated urbanization and economic development in Northwest China, the efficiency of urban wastewater treatment and the importance of water quality management have become increasingly significant. This work aims to explore urban wastewater treatment and carbon reduction mechanisms in Northwest China to alleviate water resource pressure. By utilizing online monitoring data from pilot systems, it conducts an in-depth analysis of the impacts of different wastewater treatment processes on water quality parameters.
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December 2024
Xi'an Shiyou University School of Electronic Engineering, Xi'an, 710065, China.
The expressway green channel is an essential transportation policy for moving fresh agricultural products in China. In order to extract knowledge from various records, this study presents a cutting-edge approach to extract information from textual records of failure cases in the vertical field of expressway green channel. We proposed a hybrid approach based on BIO labeling, pre-trained model, deep learning and CRF to build a named entity recognition (NER) model with the optimal prediction performance.
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December 2024
School of Computer Science and Technology (School of Cyberspace Security), Xinjiang University, Urumqi, 830046, China.
Recent works have introduced prompt learning for Event Argument Extraction (EAE) since prompt-based approaches transform downstream tasks into a more consistent format with the training task of Pre-trained Language Model (PLM). This helps bridge the gap between downstream tasks and model training. However, these previous works overlooked the complex number of events and their relationships within sentences.
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December 2024
Department of Orthopedic Surgery, National Clinical Research Center for Geriatric Disorders, Hunan Engineering Research Center of Biomedical Metal and Ceramic Implants, Xiangya Hospital, Central South University, Changsha, 410008, China.
Osteoarthritis (OA) has been the most common arthritis affecting public health all over the world. Previous experimental research reported that increased low-density lipoprotein cholesterol, along with decreased high-density lipoprotein cholesterol may be associated with increased ectopic bone formation and possible knee OA, while clinical evidence is absent. This study aimed to investigate the association between blood high-density lipoprotein cholesterol (HDL-C) and OA.
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December 2024
Klinikum Stuttgart, Stuttgart Cancer Center - Tumorzentrum Eva Mayr-Stihl DE, Kriegsbergstraße 60, Stuttgart, D-70174, Germany.
Background: Medical narratives are fundamental to the correct identification of a patient's health condition. This is not only because it describes the patient's situation. It also contains relevant information about the patient's context and health state evolution.
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