AI Article Synopsis
- * Microalgae and cyanobacteria are highlighted as promising sources for biofuels and sustainable chemicals due to their ability to perform photosynthesis, which can contribute to a carbon-neutral economy.
- * The review discusses advancements in metabolomics for these organisms, underscoring their potential as industrial cell factories for bio-based production.
Article Abstract
Metabolomics, an essential tool in modern synthetic biology based on the design-build-test-learn platform, is useful for obtaining a detailed understanding of cellular metabolic mechanisms through comprehensive analyses of the metabolite pool size and its dynamic changes. Metabolomics is critical to the design of a rational metabolic engineering strategy by determining the rate-limiting reaction and assimilated carbon distribution in a biosynthetic pathway of interest. Microalgae and cyanobacteria are promising photosynthetic producers of biofuels and bio-based chemicals, with high potential for developing a bioeconomic society through bio-based carbon neutral manufacturing. Metabolomics technologies optimized for photosynthetic organisms have been developed and utilized in various microalgal and cyanobacterial species. This review provides a concise overview of recent achievements in photosynthetic metabolomics, emphasizing the importance of microalgal and cyanobacterial cell factories that satisfy industrial requirements.
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| http://dx.doi.org/10.1016/j.biortech.2021.126196 | DOI Listing |
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