The stimulating effect of a low dose of a substance considered to be toxic is known as hormesis. The aim of this work was to use dose-response curves to evaluate the hormesis effect provided by sub-doses of the herbicide 2,4-D choline salt on the productivity of cotton at different phenological stages. The experimental design was based on randomized blocks, with four repetitions and the treatments were distributed in a 9x3 factorial design, with nine fractions of the mean label dose of the herbicide 2,4-D choline salt formulation (0 (control); 0.4275; 0.855; 1.71; 3.42; 8.55; 17.1; 34.2 and 68.4 g a.e. ha) associated with three different phenological stage of cotton, namely: V4, B4 and C4. The plants were evaluated as to the main productive parameters of the cotton plant. When applied at the V4 stage, sub-doses of the herbicide 2,4-D choline salt negatively affect the cotton crop. Sub-doses between 0.82 and 2.23 g a.e. ha of the herbicide 2,4-D choline salt applied at the B4 stage of cotton can increase all the productive variables of the crop. The productive aspects of cotton plants in the C4 stage were not influenced by the application of sub-doses of 2,4-D choline salt.
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http://dx.doi.org/10.1080/03601234.2021.1997282 | DOI Listing |
J Dairy Sci
February 2024
Balchem Corporation, Montvale, NJ 07645.
The objective of this experiment was to examine the effects of supplementation and dose of rumen-protected choline (RPC) on markers of inflammation and metabolism in liver and mammary tissue during an intramammary lipopolysaccharide (LPS) challenge. Parous Holstein cows were blocked by calving month and randomly assigned within block to receive 45 g/d of RPC (20.4 g/d of choline ions; CHOL45), 30 g/d of RPC (13.
View Article and Find Full Text PDFJ Dairy Sci
December 2023
Balchem Corporation, Montvale, NJ 07645.
Recent studies have suggested that dietary rumen-protected choline (RPC) supplementation can modulate immune function, attenuate inflammation, and improve performance in periparturient dairy cattle; however, this has yet to be evaluated during a mastitis challenge. Therefore, the objective of this study was to examine the effects of supplementation and dose of RPC on metabolism, inflammation, and performance during an intramammary lipopolysaccharide (LPS) challenge. Parous Holstein cows (parity, mean ± SD, 1.
View Article and Find Full Text PDFJDS Commun
July 2022
Balchem Corporation, New Hampton, NY 10958.
Colostrum is a critical nutrient source that provides passive immunity to dairy calves. Choline is a trimethylated molecule that is frequently supplemented in the diet to periparturient dairy cows to support postpartum health and performance. Whereas choline and its metabolites have been characterized in milk, the effects of dietary rumen-protected choline (RPC) supplementation on choline metabolites in colostrum from dairy cattle have yet to be explored.
View Article and Find Full Text PDFJ Dairy Sci
November 2022
Balchem Corporation, New Hampton, NY 10958.
The objective of this study was to examine the effects of prenatal supplementation and dose of rumen-protected choline (RPC) on neonatal calf growth, metabolism, and vaccine response. Parous Holstein cows were blocked by calving month and randomly assigned within block to receive 45 g/d of RPC [20.4 g/d of choline ions (CHOL45), n = 19], 30 g/d of RPC [13.
View Article and Find Full Text PDFJ Dairy Sci
September 2019
Department of Animal Sciences, University of Illinois, Urbana 61801; Division of Nutritional Sciences, University of Illinois, Urbana 61801. Electronic address:
Although choline requirements are unknown, enhanced postruminal supply may decrease liver triacylglycerol (TAG) storage and increase flux through the methionine cycle, helping cows during a negative energy balance (NEB). The objective was to investigate effects of postruminal choline supply during NEB on hepatic activity of betaine-homocysteine methyltransferase (BHMT), methionine synthase (MTR), methionine adenosyltransferase, transcription of enzymes, and metabolite concentrations in the methionine cycle. Ten primiparous rumen-cannulated Holstein cows (158 ± 24 d postpartum) were used in a replicated 5 × 5 Latin square design with 4-d treatment periods and 10 d of recovery (14 d/period).
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