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Bilingual language control is a dynamic cognitive system that enables individuals to effectively manage language use and prevent interference when switching between languages. Research indicates that certain neurodegenerative conditions may influence language-switching abilities or hinder the suppression of cross-language interference. However, it remains uncertain whether neurodegeneration primarily affecting mesial temporal structures, such as Mild Cognitive Impairment (MCI), impacts lexical retrieval in dual-language naming conditions.

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Background: The role of imaging in autoimmune encephalitis (AIE) remains unclear, and there are limited data on the utility of magnetic resonance imaging (MRI) to diagnose, treat, or prognosticate AIE.

Purpose: To evaluate whether MRI is a diagnostic and prognostic marker for AIE and assess its efficacy in distinguishing between various AIE subtypes.

Material And Methods: We analyzed data from 96 AIE patients from our prospective autoimmune registry.

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SEEG seizure onset patterns in mesial temporal lobe epilepsy: A cohort study with 76 patients.

Neurophysiol Clin

January 2025

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China. Electronic address:

Objectives: In the present study with a large cohort, we aimed to characterize intracerebral seizure onset patterns (SOP) of mesial temporal lobe epilepsy (mTLE), with or without hippocampal sclerosis (HS) as identified via magnetic resonance imaging (MRI).

Methods: We retrospectively analyzed 255 seizures of 76 consecutive patients with mTLE explored by stereoelectroencephalography (SEEG), including HS-mTLE (n = 52) and non-HS- mTLE (n = 24). Relevant results were obtained by a combination of spectral analysis and manual review.

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Circulating miR-134 in mesial temporal lobe epilepsy: implications in hippocampal sclerosis development and drug resistance.

Front Mol Neurosci

December 2024

UMIB-Unit for Multidisciplinary Research in Biomedicine, ICBAS- Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto, Porto, Portugal.

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Article Synopsis
  • The study investigated how metabolic brain network connectivity changes in patients with drug-resistant mesial temporal lobe epilepsy (DR-MTLE) affect surgical outcomes.
  • Patients (87) who underwent surgery were divided into seizure-free (SF) and non-seizure-free (NSF) groups, alongside a control group of healthy individuals (38).
  • Results showed that both patient groups had reduced metabolic connectivity compared to healthy controls, with the NSF group experiencing more significant disruptions, particularly in key brain networks, suggesting potential reasons for poor postoperative seizure control and implications for preoperative assessments.
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