AI Article Synopsis
- * Treatment with corticosteroids resulted in a quick improvement of his symptoms and radiographic findings.
- * Intradermal testing indicated a delayed positive reaction to the vaccine, leading to a diagnosis of COVID-19 vaccine-induced pneumonitis, likely due to Type IV hypersensitivity.
Article Abstract
A 65-year-old man experienced cough and shortness of breath 3 days after receiving the first dose of the Pfizer-BioNTech coronavirus disease 2019 (COVID-19) vaccine. Chest X-ray revealed bilateral infiltrates, and the desaturation deteriorated rapidly. The symptoms and radiographic abnormalities rapidly improved after the initiation of corticosteroid therapy. Intradermal testing of the Pfizer-BioNTech COVID-19 vaccine showed a delayed positive reaction. Based on these findings, the patient was diagnosed with COVID-19 vaccine-induced pneumonitis. The timing of the onset of pneumonitis after vaccination and the results of intradermal testing suggest that Type IV hypersensitivity against COVID-19 vaccine may have been responsible for this clinical condition.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810239 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.8310-21 | DOI Listing |
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