Objective: To describe the sociodemographic characteristics associated with e-cigarette ever use and to examine the impact of e-cigarette ever use on lung function impairment in an ageing population.

Design: A cross-sectional analysis of data from the Canadian Longitudinal Study on Aging.

Setting: A national stratified sample of 44 817 adults living in Canadian provinces.

Participants: Respondents included participants aged 45-85 and residing in the community in Canadian provinces.

Outcome Measures: The Global Lung Function Initiative normative values for forced expiratory volume in the first second (FEV), forced vital capacity (FVC), forced expiratory ratio (FEV/FVC) appropriate for age, sex, height and ethnicity were used to interpret the severity of lung function impairment. Multinomial logistic regression analysis was used to examine the impact of e-cigarette ever use on obstructive and restrictive lung function impairment.

Results: The prevalence of e-cigarette ever use was 6.5% and varied by sociodemographic factors including higher prevalence among individuals younger than 65 years, those with lower education attainment and those with lower annual household income. E-cigarette ever use was associated with 2.10 (95% CI 1.57 to 2.08) times higher odds of obstructive lung function impairment after adjusting for conventional cigarette smoking and other covariates. Individuals with exposure to e-cigarette ever use and 15 or more pack-years had 7.43 (95% CI 5.30 to 10.38) times higher odds for obstructive lung function impairment when compared with non-smokers and non-e-cigarette users after adjusting for covariates. Smokers with 15 or more pack-years had higher odds of restrictive lung function impairment irrespective of e-cigarette ever use.

Conclusions: Ever use of e-cigarettes was found to be associated with obstructive lung function impairment after adjusting for covariates, suggesting that e-cigarette use may be adding to the respiratory and other chronic disease burden in the population.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8552144PMC
http://dx.doi.org/10.1136/bmjopen-2021-051519DOI Listing

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