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Orally dissolving pilocarpine tablets for xerostomia in advanced cancer: A pilot N-of-1 feasibility study.
Palliat Med
December 2024
Palliative and Supportive Care, Mater Misericordiae Ltd., South Brisbane, QLD, Australia.
Background: Xerostomia is a common and difficult symptom experienced by patients with cancer. Pilocarpine is a cholinergic agent that stimulates salivation.
Aim: To assess the feasibility of conducting a N-of-1 trial to determine the efficacy of pilocarpine orally dissolving tablets in patients with xerostomia.
The mediating role of rumination in the relationship between negative cognitive styles and depression among pregnant women in Guangzhou, China.
Front Psychiatry
December 2024
Department of Rehabilitation, The Seventh Affiliated Hospital, Southern Medical University, Foshan, China.
Backgrounds: Negative cognitive styles (NCSs) have been identified as risk factor for the onset of depression. However, little empirical evidence is available to support its role in psychological disorders in the perinatal period. Moreover, less is known about the underlying mechanism in the relation between NCSs and depression in pregnant women.
View Article and Find Full Text PDFDevelopment and Validation of a Yoga-Based Intervention for Speech Dysfunction and Speech Difficulties Among Patients With Parkinson's Disease.
Cureus
November 2024
Integrative Medicine, Division of Yoga, Ministry of Ayush, Central Research Institute of Yoga and Naturopathy (CRIYN), Nagamangala, IND.
Introduction Parkinson's disease (PD) is primarily thought to be brought on by the death of dopaminergic neurons in the substantia nigra pars compacta of the basal ganglia. Communication difficulties are a common symptom of PD, affecting both motor speech and language systems. These challenges significantly impact the quality of life by reducing participation in communication, leading to social withdrawal, and increasing the risk of social isolation and stigma among individuals with PD.
View Article and Find Full Text PDFL-shaped relationship between atherogenic index of plasma with uric acid levels and hyperuricemia risk.
Front Endocrinol (Lausanne)
December 2024
Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Background: Hyperuricemia is a major risk factor for cardiovascular disease. This study aimed to investigate the relationship between the atherogenic index of plasma (AIP) and serum uric acid (SUA) levels, as well as the risk of hyperuricemia.
Methods: Utilizing data from the National Health and Nutrition Examination Survey (NHANES), we conducted a cross-sectional study involving 9,439 participants aged 18 years and above with complete triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) data.
A large-scale screening of hepatitis C among men who have sex with men in the community using saliva point-of-care testing.
Front Public Health
December 2024
Liver Unit, Internal Medicine Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Aim: To assess the feasibility and acceptability of massive hepatitis C virus (HCV) testing in point of care on the street using quick tests, determine the characteristics of the population included, and the prevalence of HCV infection in this population.
Methods: Cross-sectional community-based study including adult men who have sex with men (MSM) who attended the three most important LGTB+ events in Sitges (Catalonia, Spain) in 2022. Points of care were set up on tents on the street and attendees were offered voluntary anti-HCV antibody self-testing.
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