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http://dx.doi.org/10.1097/ACM.0000000000004280 | DOI Listing |
Pathology
December 2024
Department of Pathology, Amsterdam University Medical Centers/VUmc, Amsterdam, The Netherlands; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
In the course of the last decade, the pathological diagnosis of many tumours of the central nervous system (CNS) has transitioned from a purely histological to a combined histological and molecular approach, resulting in a more precise 'histomolecular diagnosis'. Unfortunately, translation of this refinement in CNS tumour diagnostics into more effective treatment strategies is lagging behind. There is hope though that incorporating the assessment of predictive markers in the pathological evaluation of CNS tumours will help to improve this situation.
View Article and Find Full Text PDFBMC Infect Dis
January 2025
Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, Belo Horizonte, Minas Gerais, Brazil.
Background: Cirrhosis has been pointed out as a clinical entity that leads to worse clinical prognosis in COVID-19 patients. However, this concept is controversial in the literature. We aimed to evaluate clinical outcomes by comparing patients with cirrhosis to those without cirrhosis in a Brazilian cohort.
View Article and Find Full Text PDFSci Rep
January 2025
College of Intelligence and Computing, Tianjin University, Tianjin, 300000, China.
Falling is an emergency situation that can result in serious injury or even death, especially in the absence of immediate assistance. Therefore, developing a model that can accurately and promptly detect falls is crucial for enhancing quality of life and safety. In the field of object detection, while YOLOv8 has recently made notable strides in detection accuracy and speed, it still faces challenges in detecting falls due to variations in lighting, occlusions, and complex human postures.
View Article and Find Full Text PDFJ Am Acad Orthop Surg
November 2024
From the Department of Orthopaedics, West Virginia University, Morgantown, WV (Sraj and Farley), and Department of Surgery, Division of Plastic Surgery, West Virginia University, Morgantown, WV (Turner and Woodberry).
Orthopaedic surgeons encounter tattoos in surgical fields with an increasing frequency and have the choice of avoiding, disregarding, bordering, or incorporating them into the surgical incisions. This article describes the history and the personal, social, and artistic value of tattoos; the physiology of tattoos and wound healing; the principles of incision planning for optimal cosmesis; and specific considerations when encountering tattoos in the surgical field. It subsequently describes cosmetic outcomes and tattoo-specific complications after surgery and provides a decision tree to help surgeons and patients decide the best approach for individual situations.
View Article and Find Full Text PDFJ Undergrad Neurosci Educ
December 2024
Berman Institute of Bioethics, Johns Hopkins University, Baltimore, MD 21205; Center for Teaching Excellence and Innovation, Johns Hopkins University, Baltimore, MD 21205.
Students are thinking about ethical, moral, and societal implications of science-as individuals and communities- regardless of whether these topics are part of formal curricula. Ethical questions can arise from broad neuroscientific questions (What is consciousness?), emerging topics (e.g.
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