Background: Adenotonsillectomy has become the primary treatment for children with sleep-disordered breathing or obstructive sleep apnea. However, few studies have investigated positional changes in the soft palate or uvula after adenotonsillectomy in children. The present study aimed to evaluate positional changes in the uvula tip using cephalometric analyses after adenotonsillectomy in children.
Methods: We analyzed 160 pediatric patients from December 2015 to July 2016, with 94 pediatric patients who underwent adenotonsillectomy as the experimental group and 66 children who were treated and followed up with frequent tonsillitis as the control group. Positional changes in the uvula tip after surgery in the adenotonsillectomy group were investigated using lateral cephalograms obtained within 1 month before surgery and 3-4 months after surgery. Two lateral cephalogram intervals for a few months in the control group who did not undergo adenotonsillectomy were analyzed.
Results: The palatal length (23.92 ± 3.47 . 24.46 ± 3.26; = 0.032), palatal angle (43.13 ± 7.76 . 46.12 ± 5.91; < 0.001), and retrouvula length (15.60 ± 3.51 . 16.60 ± 2.97; = 0.009) were significantly increased on postoperative images relative to those on preoperative images. In the control group, there was a significant change in the palatal angle (2.99 ± 5.85 . 0.27 ± 4.14; < 0.001) and retrouvula length (0.99 ± 3.64 . 0.05 ± 1.44; = 0.025), but not in the palatal length (0.58 ± 2.38 . 0.043 ± 1.26; = 0.065).
Conclusion: The findings of the present study suggest that the uvula tip is displaced in the anteroinferior direction 3 or 4 months after adenotonsillectomy in children. Thus, clinicians should be aware that the retropalatal space may expand after adenotonsillectomy in the pediatric population.
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http://dx.doi.org/10.7717/peerj.12243 | DOI Listing |
Eur Heart J Digit Health
January 2025
Department of Rehabilitation Medicine, Erasmus MC, Rotterdam, The Netherlands.
Aims: Cardiac rehabilitation (CR) shows lower effectiveness and higher dropouts among people with a low socioeconomic position (SEP) compared to those with a high SEP. This study evaluated an eHealth intervention aimed at supporting patients with a low SEP during their waiting period preceding CR.
Methods And Results: Participants with a low SEP in their waiting period before CR were randomized into an intervention group, receiving guidance videos, patient narratives, and practical tips, or into a control group.
Front Hum Neurosci
January 2025
Department of Psychology, Renmin University of China, Beijing, China.
Introduction: While considerable research in language production has focused on incremental processing during conceptual and grammatical encoding, prosodic encoding remains less investigated. This study examines whether focus and accentuation processing in speech production follows linear or hierarchical incrementality.
Methods: We employed visual world eye-tracking to investigate how focus and accentuation are processed during sentence production.
Front Bioeng Biotechnol
January 2025
Department of Orthopaedics, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Background: Microfracture drilling is a surgical technique that involves creating multiple perforations in areas of cartilage defects to recruit stem cells from the bone marrow, thereby promoting cartilage regeneration in the knee joint. Increasing the exposed bone marrow surface area (more holes in the same area) can enhance stem cell outflow. However, when the exposed area is large, it may affect the mechanical strength of the bone at the site of the cartilage defect.
View Article and Find Full Text PDFJ Adv Nurs
January 2025
Department of Behavioural Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
Aim: To develop and assess the feasibility of a nurse-led intervention aimed at improving the transition from cancer treatment to survivorship for adolescents by providing personalised information and psychosocial and self-management support.
Design: Intervention development through co-creation with adolescent patients with cancer, their parents and health care professionals, based on the MRC framework and qualitative feasibility testing.
Methods: The intervention development involved three steps: (a) identifying the problem through interviews with key stakeholders and by reviewing existing evidence on transition tools and practices; (b) designing the intervention through co-creation workshops with stakeholders and (c) assessing feasibility, acceptability and participants' experiences of the intervention through interviews with adolescents, parents, healthcare professionals and teachers.
Nucleic Acids Res
January 2025
Laboratory of Structural and Functional Organization of Chromosomes, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov St., 119334 Moscow, Russia.
Dictyostelium discoideum is a unicellular slime mold, developing into a multicellular fruiting body upon starvation. Development is accompanied by large-scale shifts in gene expression program, but underlying features of chromatin spatial organization remain unknown. Here, we report that the Dictyostelium 3D genome is organized into positionally conserved, largely consecutive, non-hierarchical and weakly insulated loops at the onset of multicellular development.
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