Background: Up to 25% of the total coronavirus disease 2019 (COVID-19) admissions comprise patients with comorbidities who present to the emergency department (ED) with only mild-to-moderate disease. It is unclear whether as an alternative to hospitalization, telemedicine can be used to monitor these "high-risk" comorbid patients. The aim of our study was to answer this question by comparing the outcome of such patients discharged under a family medicine service (FMS) telemonitoring program and those admitted to hospital.
Materials And Methods: Patients with three or more risk factors for progression to severe COVID-19 disease were designated as "high-risk" in our study. In the absence of acute indication for hospitalization, these high-risk patients with mild-to-moderate disease were discharged home under the supervision of FMS led telemonitoring between October 2020 and February 2021 and were labelled as "Telemedicine group." They were compared to similar patients who were admitted to hospital between March-August 2020 before the implementation of telemedicine service (TMS) and were taken as "Control group." Outcome measures included intubation, number of inpatient days, 28-day mortality and cost analysis for the two groups.
Results: Out of 572 COVID-19 patients who presented to the ED, 70 met the inclusion criteria for the "Telemedicine Group" and 35 were included in the "Control Group". In the Telemedicine group, 21 (30.0%) patients were brought back to ED for re-evaluation and 16 (22.9%) were eventually admitted to the hospital. There was no difference in terms of oxygen requirements, intubation, and intensive care unit admission ( > 0.74) between the groups, and none of the study patients died. The Family Medicine-led TMS saved 77% inpatient admissions and on average 4.4 hospital days and $3400 per patient ( < . 0001).
Conclusion: Family medicine-led telemonitoring of high-risk COVID-19 patients presenting to the ED with mild-to-moderate disease is a feasible and cost-effective alternative to hospitalization.
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http://dx.doi.org/10.4103/jfcm.jfcm_184_21 | DOI Listing |
Pak J Med Sci
January 2025
Meijin Yuan Department of Nursing, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei, China.
Objective: To explore the clinical efficacy of the interactive humanistic nursing model in emergency rescue of epidemic outbreaks.
Methods: This was a retrospective study. A total of 200 patients with novel coronavirus pneumonia (NCP) admitted to The First Affiliated Hospital of Hebei North University between December 2022 and March 2023 were selected and divided into the observation group(n=100) and the control group(n=100) according to different nursing methods used.
Front Pediatr
January 2025
Division of Neonatology, Department of Pediatrics, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Background: Multisystem inflammatory syndrome in neonates (MIS-N) is a rare condition thought to be associated with prenatal exposure to maternal severe acute respiratory syndrome coronavirus 2 infection. This immune-mediated hyperinflammation has been described in neonates with multiorgan dysfunction, including cardiopulmonary, encephalopathy, coagulopathy, and vascular complications. However, renovascular complications in MIS-N are rare.
View Article and Find Full Text PDFPNAS Nexus
January 2025
Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Here, we present Link-Seq, a highly efficient droplet microfluidic method for combined sequencing of antibody-encoding genes and the transcriptome of individual B cells at large scale. The method is based on 3' barcoding of the transcriptome and subsequent single-molecule PCR in droplets, which freely shift the barcode along specific gene regions, such as the antibody heavy- and light-chain genes. Using the immune repertoire of COVID-19 patients and healthy donors as a model system, we obtain up to 91.
View Article and Find Full Text PDFJ Asthma Allergy
January 2025
Department of Thoracic Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Background: Non-pharmaceutical interventions (NPIs) were widely used during the coronavirus disease 2019 (COVID-19) pandemic, however their impact on acute asthma exacerbations (AEs) is not well studied.
Methods: We had retrospectively collected patients with asthma AEs between 2019 and 2020 and retrieved data from the Chang Gung Research Database, including clinical manifestations, medications, pulmonary function, clinic and emergency department visits and hospitalizations.
Results: A total of 39,108 adult patients with asthma were enrolled, of whom 1502 were eligible for analysis.
J Int Soc Prev Community Dent
December 2024
Assistant professor, Oral and Dental Disease Research Center, Department of Operative Dentistry, Faculty of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran.
Aim: Tooth sensitivity caused by exposed dentin tubules is a common clinical problem requiring correct treatment methods. Owing to the spread of the COVID-19 virus, it has become common to use different mouthwashes, including 1.5% hydrogen peroxide (HP), before dental procedures.
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