AI Article Synopsis
- - Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, fast-growing, and pigmented tumor arising from neural crest cells, with a high rate of recurrence despite being classified as benign.
- - Early diagnosis is crucial to prevent local growth because MNTI can resurface mainly due to incomplete removal during surgery or its tendency to occur in multiple locations.
- - The case study highlights a 7-month-old boy with an MNTI in the maxilla that was completely excised with no recurrence after one year; it also reviews existing literature on the tumor’s characteristics and treatment options, including surgery, radiotherapy, and chemotherapy.
Article Abstract
Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, fast-growing, pigmented neoplasm of neural crest origin. Despite of its rapid and locally infiltrative growth, it is still considered benign with high recurrence rate and malignant potential, so early diagnosis is extremely important to limit its local expansion. Recurrences can be expected primarily because of incomplete excision, tumor dissemination, or due to its multicentric nature. We report a case of MNTI originating in the maxilla of a 7-month-old male infant, which was managed with complete surgical excision of the tumor, with no signs of recurrence after a 1-year follow-up period. In addition, a complete literature review has been reported, in an attempt to understand the origin, histopathologic and immunohistochemistry features with surgical modalities and advantages of radiotherapy and chemotherapy in cases where complete surgical extirpation is questionable.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491329 | PMC |
| http://dx.doi.org/10.4103/0973-029X.325239 | DOI Listing |
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