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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651071 | PMC |
| http://dx.doi.org/10.1161/CIRCULATIONAHA.121.056534 | DOI Listing |
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Study on Highly Sensitive Capacitive Pressure Sensor Based on Silk Fibroin-Lignin Nanoparticles Hydrogel.
Biomacromolecules
January 2025
Hubei Provincial Key Laboratory of Green Materials for Light Industry, Hubei University of Technology, Wuhan 430068, China.
Silk fibroin (SF) hydrogel has been proven to have excellent applications in the field of pressure sensors, but its sensing performance still needs improvement. A flexible hydrogel prepared from natural macromolecular materials was developed, and lignin nanoparticles (LNPs) were introduced during the preparation of the SF hydrogel. When LNPs account for 3% of SF, the sensing unit of the SF-LNPs hydrogel exhibits high stress sensitivity (1.
View Article and Find Full Text PDFActivation and memory of the heatshock response is mediated by Prion-like domains of sensory HSFs in Arabidopsis.
Mol Plant
January 2025
Leibniz Institut für Gemüse und Zierpflanzenbau (IGZ) e.V., Großbeeren, Germany; Institute of Biochemistry and Biology, University of Potsdam, Potsdam, Germany. Electronic address:
Plants are able to sense and remember heat stress. An initial priming heat stress enables plants to acclimate so that they are able to survive a subsequent higher temperature. The heatshock transcription factors (HSFs) play a crucial role in this process, but the mechanisms by which plants sense heat stress are not well understood.
View Article and Find Full Text PDFTranscriptional regulation of miR528-PPO module by miR156 targeted SPLs orchestrates chilling response in banana.
Mol Hortic
January 2025
Guangdong Provincial Key Laboratory of Applied Botany, Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, 510650, Guangzhou, China.
Banana is sensitive to cold stress and often suffers from chilling injury with browning peel and failure to normal ripening. We have previously reported that banana chilling injury is accompanied by a reduction of miR528 accumulation, alleviating the degradation of its target gene MaPPO and raising ROS levels that cause peel browning. Here, we further revealed that the miR528-MaPPO cold-responsive module was regulated by miR156-targeted SPL transcription factors, and the miR156c-MaSPL4 module was also responsive to cold stress in banana.
View Article and Find Full Text PDFA Self-Supporting Flexible Electrode for Tracking and Reversible Quantification of Mg2+ and Ca2+ in the Brains of Freely Behaving Animal.
Angew Chem Int Ed Engl
January 2025
East China Normal University, Dept. of Chemistry, Dongchuan Road 500, 200062, Shanghai, CHINA.
Monitoring dynamic neurochemical signals in the brain of free-moving animals remains great challenging in biocompatibility and direct implantation capability of current electrodes. Here we created a self-supporting polymer-based flexible microelectrode (rGPF) with sufficient bending stiffness for direct brain implantation without extra devices, but demonstrating low Young's modulus with remarkable biocompatibility and minimal position shifts. Meanwhile, screening by density functional theory (DFT) calculation, we designed and synthesized specific ligands targeting Mg2+ and Ca2+, and constructed Mg-E and Ca-E sensors with high selectivity, good reversibility, and fast response time, successfully monitoring Mg2+ and Ca2+ in vivo up to 90 days.
View Article and Find Full Text PDFImpact of pathological complete response on survival in gastric cancer after neoadjuvant chemotherapy: a propensity score matching analysis.
BMC Gastroenterol
January 2025
Department of General Surgery (Gastrointestinal Surgery, Unit 1), The Sixth Affiliated Hospital, Sun Yat-sen University, 26 Yuancun Erheng Road, Guangzhou, 510655, China.
Purpose: The survival benefits of neoadjuvant chemotherapy (NAC) for locally advanced gastric cancer (LAGC) patients are inconsistent. This study aims to investigate how different tumor regression grades (TRG) influence the survival gains associated with NAC treatment.
Methods: This study compared the treatment outcomes of patients who underwent CSC (neoadjuvant chemotherapy - surgery - adjuvant chemotherapy) with those receiving traditional SC (surgery - adjuvant chemotherapy) treatment.
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