AI Article Synopsis
- Perineural extension is a serious complication of skin, mucosal, and salivary gland tumors, leading to worse outcomes.
- MRI with advanced 3D contrast-enhanced techniques is effective for detecting this extension, particularly involving the trigeminal and facial nerves.
- PET/CT scans can help locate primary tumors or recurrence but are most effective when used alongside MRI; CT scans also assist in improving specificity and planning for surgeries.
Article Abstract
Perineural extension is an increasingly recognized pathway of extension of cutaneous, mucosal, and salivary gland neoplasms associated with a severe adverse prognosis. Imaging identification is feasible by MR imaging 3-dimensional contrast-enhanced submillimetric sequences. The trigeminal nerve branches and facial nerve are the most commonly involved. PET with computed tomography may aid in the identification of the primary tumor location or recognition of recurrence, but only in conjunction with MR imaging does it achieve similar detection rates for perineural extension. Computed tomography scanning is an adjunct to MR imaging to increase specificity and for surgical treatment planning.
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| http://dx.doi.org/10.1016/j.nic.2021.05.007 | DOI Listing |
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