This study examined the efficacy of CVLT-3 response bias (i.e., parametric and nonparametric response bias) indices in differentiating between a clinical sample with traumatic brain injury and a litigating sample with poor performance validity. Participants included 106 individuals, divided into two groups: clinical group with TBI ( = 56) and a litigating group who demonstrated inadequate performance validity ( = 50), as measured by failure on at least two performance validity tests. Archival CVLT-II data was rescored utilizing the CVLT-3 scoring and normative data. Receiver operator characteristic (ROC) curve analysis was used to evaluate the diagnostic discriminability of the two response bias indices. Both parametric and nonparametric bias indices showed acceptable levels of diagnostic discrimination: AUC = .791 for parametric response bias and AUC = .753 for nonparametric response bias. Parametric response bias' discrimination was statistically superior to the nonparametric responses bias' discrimination. The CVLT-3 response bias score demonstrated good sensitivity and specificity when differentiating between individuals in a clinical sample with TBI and individuals in litigation who demonstrated inadequate performance validity.
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http://dx.doi.org/10.1080/13854046.2021.1993347 | DOI Listing |
J Neuroeng Rehabil
January 2025
Luzerner Kantonsspital, University, Teaching and Research Hospital, University of Lucerne, Lucerne, Switzerland.
Background: Construct validity and responsiveness of upper limb outcome measures are essential to interpret motor recovery poststroke. Evaluating the associations between clinical upper limb measures and sensor-based arm use (AU) fosters a coherent understanding of motor recovery. Defining sensor-based AU metrics for intentional upper limb movements could be crucial in mitigating bias from walking-related activities.
View Article and Find Full Text PDFNat Aging
January 2025
Translational Science and Therapeutics Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Somatic stem cell pools comprise diverse, highly specialized subsets whose individual contribution is critical for the overall regenerative function. In the bone marrow, myeloid-biased hematopoietic stem cells (myHSCs) are indispensable for replenishment of myeloid cells and platelets during inflammatory response but, at the same time, become irreversibly damaged during inflammation and aging. Here we identify an extrinsic factor, semaphorin 4A (Sema4A), which non-cell-autonomously confers myHSC resilience to inflammatory stress.
View Article and Find Full Text PDFSci Rep
January 2025
Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary.
A key question about social media use is whether it constitutes an addiction. A possible frame of reference to investigate this question is the Incentive Sensitizations Theory (IST), as it provides a solid empirical background to understand the motivational and hedonic aspects of problematic behaviors. A central assumption of IST that addiction-related cues play a pivotal role in addictive behaviors has remained relatively understudied in the context of social media use.
View Article and Find Full Text PDFCochrane Database Syst Rev
January 2025
Department of Psychiatry and Department of Epidemiology and Biostatistics, Western University, St Thomas, Canada.
Background: Generalised anxiety disorder (GAD) is a mental health condition characterised by excessive anxiety and worry about everyday events. GAD is a common disorder and generally affects women twice as often as men. Treatments include various psychological and pharmacological therapies.
View Article and Find Full Text PDFCodas
January 2025
Programa de Pós-Graduação em Fonoaudiologia, Universidade Estadual Paulista "Júlio de Mesquita Filho" - UNESP - Marília (SP), Brasil.
Purpose: To investigate whether there is a difference in the classification of speech hypernasality by inexperienced listeners using different ordinal scales; to verify the agreement of the listeners in the analyses when using these scales; and to verify whether the order in which the scales are presented influences the results.
Methods: Twenty Speech-Language Pathology students classified the degrees of hypernasality of 40 (oral) samples from patients with cleft lip and palate. Ten performed the classifications using a 4-point scale (absent, mild, moderate, and severe) and, after two weeks, using a 3-point scale (absent, slightly hypernasal, and very hypernasal).
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