AI Article Synopsis
- Mycobacterium marseillense is a newly identified species within the Mycobacterium avium complex, with limited human infections reported globally.
- A case in Japan involved tenosynovitis in an immunocompetent adult, where the bacteria was first misidentified as M. intracellulare using PCR, later confirmed as M. marseillense through genetic sequencing and MALDI-TOF MS.
- The study highlights the potential for underreporting M. marseillense infections due to its resemblance to M. intracellulare, suggesting that MALDI-TOF MS can serve as a quick and effective diagnostic tool.
Article Abstract
Background: Mycobacterium marseillense is a new species of the Mycobacterium avium complex. There has been only a few human infections caused by M. marseillense worldwide.
Case Presentation: We report a case of tenosynovitis caused by M. marseillense in an immunocompetent adult in Japan. The isolate was initially identified as M. intracellulare using commercial real time polymerase chain reaction assays and later identified as M. marseillense with sequencing of the the rpoB and hsp65 regions, and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).
Conclusions: This is the first case reporting on M. marseillense generating a positive result with commercial real time PCR assays targeting MAC. Human infections associated by M. marseillense might be underreported due to similarities with Mycobacterium intracellulare. To accurately identify M. marseillese, MALDI-TOF MS might provide a rapid and reliable method.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542306 | PMC |
| http://dx.doi.org/10.1186/s12879-021-06770-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Pain around the first ray of the hand: differential diagnoses and treatment].
Orthopadie (Heidelb)
January 2025
Klinik für Handchirurgie und Orthopädie, Spital Langenthal, Spital Region Oberaargau SRO AG, Langenthal, Schweiz.
Pain around the first ray of the hand, particularly in the thumb area, is a frequent clinical problem that can have various causes. This article explores the most important differential diagnoses, including thumb carpometacarpal (CMC-I) osteoarthritis (rhizarthrosis), de Quervain's stenosing tenosynovitis, carpal tunnel syndrome and Wartenberg's syndrome. A detailed medical history, targeted clinical examination and if necessary the use of modern imaging techniques are crucial for making the diagnosis.
View Article and Find Full Text PDFUnusual swelling of the hand and multiple nodules over the body - beware of mycobacteria.
Acta Orthop Belg
December 2024
Atypical mycobacteria can cause rare and atypical infections of the hand. We report the case of an immunocompetent 46-year-old male initially presenting with thumb felon and progressively developing symptoms of carpal tunnel syndrome, tenosynovitis of multiple fingers and a sporotrichoid lymphocutaneous infection causing chronic cutaneous lesions all over the body. We would like to highlight the diagnostic and therapeutic difficulties of these atypical infections, which mimic other conditions and can cause a lot of morbidity.
View Article and Find Full Text PDFSupernumerary Muscles in the Leg and Foot: A Review of Their Types, Frequency, and Clinical Implications.
J Am Podiatr Med Assoc
January 2025
*Western University of Health Sciences, College of Podiatric Medicine, Pomona, CA.
Variations of the ankle anatomy are infrequent and exist as supernumerary muscles and tendons. Often understudied and overlooked, their presence can cause many complications of the lower extremity. These muscles, although often asymptomatic, can cause great pain and complications such as tenosynovitis, tarsal tunnel syndrome, lateral ankle instability, and ankle pain when they impinge on the normal anatomy of the patient.
View Article and Find Full Text PDFDe Quervain's Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report.
Case Rep Infect Dis
January 2025
Division of Pediatric Infectious Diseases, Virginia Commonwealth University Health System, Richmond, Virginia, USA.
We present the case of a fully vaccinated 39-year-old male with no pertinent past medical history who initially presented with De Quervain's tenosynovitis which was successfully treated with a corticosteroid injection. His symptoms recurred during a COVID-19 infection, which was treated with a repeat corticosteroid injection. Symptoms recurred during an influenza infection and were subsequently treated with a first dorsal compartment release.
View Article and Find Full Text PDFCharacterization and pathogenicity of a novel avian orthoreovirus in China.
Front Microbiol
January 2025
College of Animal Science, South China Agricultural University, Guangzhou, China.
Introduction: Avian orthoreovirus (ARV) is a significant pathogen causing viral arthritis, leading to substantial economic losses in the poultry industry worldwide.
Methods: A novel ARV strain, designated FJ202311, was isolated from a broiler farm in Fujian Province, China. Whole-genome sequencing was conducted using next-generation sequencing with MGI technology, and phylogenetic analysis of the sigma C amino acid sequence was performed.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!