Uncertainty around the Long-Term Implications of COVID-19.

Pathogens

Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.

Published: October 2021

AI Article Synopsis

  • SARS-CoV-2 has led to over 231 million infections and 4.7 million deaths globally as of late September 2021.
  • Some countries have implemented strict Zero COVID policies to keep infection rates near zero, while others in Europe and North America have opted for varying mitigation strategies to protect health systems.
  • The text discusses the long-term risks associated with COVID-19, including potential for viral mutations, persistent infections, reinfections, immune issues, and complications like Long COVID.

Article Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 231 million people globally, with more than 4.7 million deaths recorded by the World Health Organization as of 26 September 2021. In response to the pandemic, some countries (New Zealand, Vietnam, Taiwan, South Korea and others) have pursued suppression strategies, so-called Zero COVID policies, to drive and maintain infection rates as close to zero as possible and respond aggressively to new cases. In comparison, European countries and North America have adopted mitigation strategies (of varying intensity and effectiveness) that aim primarily to prevent health systems from being overwhelmed. With recent advances in our understanding of SARS-CoV-2 and its biology, and the increasing recognition there is more to COVID-19 beyond the acute infection, we offer a perspective on some of the long-term risks of mutational escape, viral persistence, reinfection, immune dysregulation and neurological and multi-system complications (Long COVID).

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536991PMC
http://dx.doi.org/10.3390/pathogens10101267DOI Listing

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