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Acute Toxicity, Immunotoxicity and Allergenicity of Protease Complex Obtained from Micromycete . | LitMetric
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Acute Toxicity, Immunotoxicity and Allergenicity of Protease Complex Obtained from Micromycete .

Svetlana Alipkina Elena Kornienko Denis Nalobin Alexander Osmolovskiy

Pharmaceutics

Biological Faculty, M.V. Lomonosov Moscow State University, 119234 Moscow, Russia.

Published: October 2021

The different effects on animals of the thrombolytic protease complex of the new producer 203 were studied. The tests of acute toxicity, immunotoxicity and allergenicity should conclude that the studied proteolytic complex is safe for medical usage. For the intravenous and the intraperitoneal routes of administration, the maximum tolerated dose and the median lethal dose were not determined.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539265PMC
http://dx.doi.org/10.3390/pharmaceutics13101660DOI Listing

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