The normative transition to formal schooling confronts children with social challenges but also opportunities. Longitudinal research on how school entry impacts children's family and friend-ship relationships is scarce. This study investigated social relationship qualities with parents, siblings, and friends among 1110 children (49.9% female) from the prospective, population-based Bavarian Longitudinal Study at 6 years (before school entry) and 8 years using a forced-choice card-sorting task. Multivariate analyses of variance revealed significant effects of age (i.e., school entry) on social relationship qualities with mothers (Pillai's Trace (PT) = 0.28, (9, 1101) = 47.73, < 0.001), fathers (PT = 0.14, (9, 1101) = 19.47, < 0.001), siblings (PT = 0.27, (9, 1101) = 46.14, < 0.001), and friends (PT = 0.21, (9, 1101) = 32.57, < 0.001). On average, children reported higher levels of parental comfort after school entry. Companionable qualities increased in relationships with friends, whereas sibling relationships became more conflictual from preschool to early school age. Findings provide unique insights into how social relationships develop from preschool to early school age, supporting evidence of the growing importance of friends. Conflict was predominant and increasing in sibling relationships and should be considered more in future research.
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http://dx.doi.org/10.3390/children8100891 | DOI Listing |
Front Public Health
March 2025
Department of Nursing, College of Health Science, Mattu University, Mattu, Ethiopia.
Background: Podoconiosis is non-filarial lymphoedema of the lower extremities. It impairs individuals' overall lives, including their health, economy, psychology, and social interactions. Podoconiosis is a preventable and effectively manageable disease.
View Article and Find Full Text PDFJ Hum Nutr Diet
April 2025
Iowa State University, Ames, Iowa, USA.
Introduction: Integrating systems thinking, which emphasizes recognizing interconnections, gaining diverse perspectives and considering the big picture, can enhance curricula and better prepare practitioners. Despite its benefit and growing support, systems thinking is not yet a required part of dietetics accreditation or entry-level practice. This qualitative study sought to understand educators' views on incorporating systems thinking into nutrition and dietetics education.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
March 2025
Kobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China.
CXCR4 (CXC chemokine receptor type 4), a member of the G protein-coupled receptor superfamily, plays a role in cell migration and functions as a coreceptor for HIV entry. Molecular therapeutics targeting CXCR4 have been under intensive investigation. To date, only two small-molecule antagonist drugs targeting CXCR4, plerixafor (AMD3100) and mavorixafor (AMD070), have been approved.
View Article and Find Full Text PDFPLoS One
March 2025
Department of Laboratory Medicine, Peking University Shenzhen Hospital, Shenzhen, China.
Objective: Point-of-care testing (POCT) blood glucose meters provide rapid and convenient monitoring for clinical care and chronic disease management. However, their accuracy is often compromised by risks associated with personnel, equipment, and procedural inconsistencies. This study systematically assesses these risks using the Failure Mode and Effects Analysis (FMEA) method and proposes control measures aligned with ISO 15189:2022 standards.
View Article and Find Full Text PDFPLoS Negl Trop Dis
March 2025
Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Arthropod-borne viruses (arboviruses) constitute a significant ongoing public health threat, as the mechanisms of pathogenesis remain incompletely understood. Cardiovascular symptomatology is emerging as an important manifestation of arboviral infection. We have recently studied the cardiac tropism implicated in cardiac infection in mice for the alphavirus chikungunya virus (CHIKV), and we therefore sought to evaluate the cardiac tropism of other emerging alphaviruses and arboviruses.
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