Canine ADHD-like behavior is a behavioral problem that often compromises dogs' well-being, as well as the quality of life of their owners; early diagnosis and clinical intervention are often critical for successful treatment, which usually involves medication and/or behavioral modification. Diagnosis mainly relies on owner reports and some assessment scales, which are subject to subjectivity. This study is the first to propose an objective method for automated assessment of ADHD-like behavior based on video taken in a consultation room. We trained a machine learning classifier to differentiate between dogs clinically treated in the context of ADHD-like behavior and health control group with 81% accuracy; we then used its output to score the degree of exhibited ADHD-like behavior. In a preliminary evaluation in clinical context, in 8 out of 11 patients receiving medical treatment to treat excessive ADHD-like behavior, H-score was reduced. We further discuss the potential applications of the provided artifacts in clinical settings, based on feedback on H-score received from a focus group of four behavior experts.
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http://dx.doi.org/10.3390/ani11102806 | DOI Listing |
FEBS J
December 2024
Research Center for Pharmaceutical Development, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Yakugaku Zasshi
December 2024
Department of Pharmacology, Faculty of Pharmaceutical Science, Health Sciences University of Hokkaido.
J Clin Child Adolesc Psychol
October 2024
Department of Psychiatry and Behavioral Sciences and MIND Institute, University of California.
Objective: Self-regulation abilities in childhood are predictive of a range of challenges later in life, making it important to identify difficulties in this area as early as possible. Autistic children and those with attention-deficit/hyperactivity disorder (ADHD) often have difficulties with self-regulation, but little is known about the similarities and differences in such abilities across neurodevelopmental conditions.
Method: We examined self-regulation using a delay of gratification task in 36-month-old autistic children ( = 20), those showing clinically relevant concerns for ADHD (i.
Biomolecules
July 2024
Department of Pharmacology, Oxford University, Oxford OX1 3QT, UK.
The impaired function of the serotonin transporter (SERT) in humans has been linked to a higher risk of obesity and type 2 diabetes, especially as people age. Consuming a "Western diet" (WD), which is high in saturated fats, cholesterol, and sugars, can induce metabolic syndrome. Previous research indicated that mice carrying a targeted inactivation of the gene (knockout, KO) and fed a WD display significant metabolic disturbances and behaviors reminiscent of ADHD.
View Article and Find Full Text PDFEnviron Int
September 2024
Key Laboratory of Environmental Stress and Chronic Disease Control & Prevention (China Medical University), Ministry of Education, PR China; Department of Health Laboratory Technology, School of Public Health, China Medical University, Shenyang 110122, PR China. Electronic address:
Triclosan (TCS) is an environmental pollutant. In recent years, there has been increasing level of concern regarding the potential toxicity of TCS in animals and humans, especially its effects on the nervous system. However, whether TCS induces ADHD-like behaviour and the mechanism by which it affects neural function are unclear.
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