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Cross-sectional imaging of speed-of-sound distribution using photoacoustic reversal beacons.
Photoacoustics
February 2025
School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China.
Photoacoustic tomography (PAT) enables non-invasive cross-sectional imaging of biological tissues, but it fails to map the spatial variation of speed-of-sound (SOS) within tissues. While SOS is intimately linked to density and elastic modulus of tissues, the imaging of SOS distribution serves as a complementary imaging modality to PAT. Moreover, an accurate SOS map can be leveraged to correct for PAT image degradation arising from acoustic heterogeneities.
View Article and Find Full Text PDFInjectable Fluorescent Bottlebrush Polymers for Interventional Procedures and Biomedical Imaging.
Biomacromolecules
January 2025
Department of Chemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, United States.
Injectable biomaterials play a vital role in modern medicine, offering tailored functionalities for diverse therapeutic and diagnostic applications. In ophthalmology, for instance, viscoelastic materials are crucial for procedures such as cataract surgery but often leave residues, increasing postoperative risks. This study introduces injectable fluorescent viscoelastics (FluoVs) synthesized via one-step controlled radical copolymerization of oligo(ethylene glycol) acrylate and fluorescein acrylate.
View Article and Find Full Text PDFMechanically Triggered Protein Desulfurization.
J Am Chem Soc
January 2025
New Cornerstone Science Laboratory, Tsinghua-Peking Joint Center for Life Sciences, Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic and Systems Biology, Department of Chemistry, Tsinghua University, Beijing 100084, China.
The technology of native chemical ligation and postligation desulfurization has greatly expanded the scope of modern chemical protein synthesis. Here, we report that ultrasonic energy can trigger robust and clean protein desulfurization, and we developed an ultrasound-induced desulfurization (USID) strategy that is simple to use and generally applicable to peptides and proteins. The USID strategy involves a simple ultrasonic cleaning bath and an easy-to-use and easy-to-remove sonosensitizer, titanium dioxide.
View Article and Find Full Text PDFRisk factors and prognosis analysis of dysphagia after occipitocervical fusion surgery: a retrospective study of 43 cases.
J Orthop Surg Res
January 2025
Department of Spine Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350004, China.
Objectives: To analyze the risk factors for developing dysphagia after occipitocervical fusion (OCF) and investigate possible mechanisms and prognosis.
Methods: The case data of 43 patients who underwent OCF were retrospectively reviewed. Patients were divided into group A (dysphagia group) and group B (non-dysphagia group) based on Bazaz scoring criteria.
Clinical application of third-generation dual-source CT-based dynamic imaging reconstruction for pulmonary embolism imaging.
J Cardiothorac Surg
January 2025
Department of Thyroid Breast Cardiothoracic & Vascular Surgery, Beibei District Hospital of Traditional Chinese Medicine, No. 380 Jiangjun Road, Beibei District, Chongqing, 400700, China.
Background: To evaluate the clinical diagnostic value of third-generation dual-source CT for pulmonary embolism, focusing on the optimization of dual-source CT scanning with dynamic reconstruction in acute pulmonary embolism (PE) and various imaging manifestations.
Methods: Eighty-two patients with pulmonary embolism were enrolled and randomly divided into standard CT angiography (SCTA) and dynamic CT angiography (DCTA). DCTA patients were divided into dynamic CT angiography arterial phase (DCTAa), time phase Angiography reconstruction (TMIP-CTA), and 4D noise reduction TMIP-CTA according to the image reconstruction.
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