Marked prognostic differences exist between the two cutaneous lesions: squamous cell epithelioma and keratoacanthoma. The former may affect the vital prognosis while the latter usually heals spontaneously. Early diagnosis is therefore of the utmost importance, but clinico-pathologic discordances can exist when a first intention partial biopsy does not provide histologic data essential for diagnosis, or as a result of misleading clinical forms. Wide excision of these lesions is therefore an immediate necessity.
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