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alginate lyase and Psl glycoside hydrolase inhibit biofilm formation by CF2843 on three-dimensional aggregates of lung epithelial cells.
Biofilm
June 2025
CSIR- Institute of Microbial Technology, Sector 39-A, Chandigarh, 160036, India.
is an opportunistic pathogen that produces a biofilm containing the polysaccharides, alginate, Psl, and Pel, and causes chronic lung infection in cystic fibrosis patients. Others and we have previously explored the use of alginate lyases in inhibiting biofilm formation on plastic and lung epithelial cell monolayers. We now employ a more physiologically representative model system, i.
View Article and Find Full Text PDFHepatitis A-associated jaundice, intermittent abdominal pain, and hepatic cystic mass: case report.
J Surg Case Rep
March 2025
Surgery Department, Security Force Hospital, Al Riyadh, Saudi Arabia.
Mucinous cystic neoplasms of the liver are mostly benign but state challenging clinical problems. The case report emphasizes the need for thorough assessment and surgery intervention in patients with hepatic cystic masses in the context of potential biliary complications. A 21-year-old female patient presented with jaundice, minimal pruritus, and episodic right upper quadrant pain and a recent history of hepatitis A infection raised the initial concern.
View Article and Find Full Text PDFExploring the Enigma of a Urachal Mucinous Cystic Tumor of Low Malignant Potential (MCTLMP): A Case Report and Literature Review.
Cureus
February 2025
Department of Pathology, Antwerp University Hospital, Edegem, BEL.
Mucinous urachal neoplasms are rare and can present as benign cystadenomas, mucinous cystic tumors of low malignant potential (MCTLMPs), or invasive adenocarcinomas. MCTLMPs occupy a borderline category characterized by mild-to-moderate atypia and papillary/villous architecture without stromal invasion. Here, we describe a 54-year-old male patient who presented with persistent dysuria and was found to have a vesicourachal diverticulum.
View Article and Find Full Text PDFBowel Obstruction Due to the Mesenteric Mass Being an Enteritis Cystica Profunda: A Case Report.
Cureus
February 2025
Hepatobiliary Surgery, Prince Sultan Military Medical City, Riyadh, SAU.
Enteritis cystica profunda (ECP) is a rare benign condition characterized by mucin-filled cystic spaces in the submucosal layer of the small intestine. It is often associated with inflammatory conditions, such as Crohn's disease. This case report describes a 47-year-old male with a history of diabetes and hypertension who presented with flank pain and dysuria.
View Article and Find Full Text PDFDiagnostic Value of Cytology in Pancreatic Endoscopic Ultrasound-Guided Fine Needle Aspiration: Accuracy in Common Epithelial Pancreatobiliary Tumors and the Role of Cell Block Analysis.
Iran J Pathol
January 2025
Department of Biostatistics, Shiraz University of Medical Sciences, Shiraz, Iran.
Background & Objective: Limited literature describes the accuracy of endoscopic ultrasonography-fine needle aspiration (EUS-FNA) cytology in various types of pancreatic epithelial tumors, and this underscores the usefulness of cell blocks, and highlights potential diagnostic pitfalls.
Methods: This study included 108 patients who underwent EUS-FNA pancreatobiliary cytology followed by surgery. Age, gender, tumor location, tumor size, presence or absence of a cell block, cytologic and pathologic diagnoses, and histologic tumor grade were recorded.
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