AI Article Synopsis
- Plant-derived medicines are gaining popularity in both traditional and modern medicine, particularly in developing countries, with a focus on the widespread use of a specific plant, which this review explores.
- The review collected data from numerous databases to evaluate the ethnotherapeutic applications and phytochemical composition of the plant, noting that it is predominantly used for gastrointestinal disorders and that the leaves are most commonly utilized.
- A total of 502 phytochemicals were identified in various parts of the plant, with terpenes and phenolic compounds being the most prevalent categories, highlighting the need for further pharmacological investigation of these compounds before clinical application.
Article Abstract
Background: Plant-derived medicines are widespread and continue to increase in traditional and modern medicine, especially in developing countries. L. is among the most used plants in conventional medication worldwide. This review aimed to highlight the ethnotherapeutic uses and phytochemical status of identified compounds in . .
Methods: Data were collected from Google Scholar, PubMed/Medline, SciFinder, Science Direct, Scopus, the Wiley Online Library, Web of Science, and any other helpful search engine using as the primary keyword.
Results: Some countries, worldwide, use . in their traditional medicine system to manage diverse ailments, mainly diseases and gastrointestinal tract disorders (25.33%). Leaf was the mostly used part (49.28%), prepared by decoction (31.58%) and overall administrated orally (53.57%) as the main route of admission. Around 502 phytoconstituents were identified in different plant parts, especially fruit (38.19%) ethanol/ethyl acetate extract. In most cases (36.17%), the solvent of the extract was not specified. Several phytochemical classes were found in the plant, especially terpenes (26.09%) and phenolic compounds (14.94%). Esters were also abundant (11.55%). In the terpenes category, carotenoids were the most abundant (11.15% followed by monoterpenes (8.76%) and diterpenes (3.18%). However, flavonoids (5.17%) followed by cinnamic acid derivatives (3.99%), monophenolic compounds (1.79%), and phenolic acids (1.33 M) are the most reported phenolic compounds. Hexadecanoic acid (palmitic acid) was the most cited (five times).
Conclusion: . plays an essential role in managing diseases in some countries and is rich in chemical compounds, which need to be isolated and investigated pharmacologically before clinical trials.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523295 | PMC |
| http://dx.doi.org/10.1155/2021/5212348 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Characterization, Anti-glycation, Anti-inflammation, and Lipase Inhibitory Properties of Rauvolfia vomitoria Leaf Extract: In Vitro and In Silico Evaluations for Obesity Treatment.
Appl Biochem Biotechnol
October 2024
Department of Biochemistry, Faculty of Science, Delta State University, P.M.B.001, Abraka, Nigeria.
Article Synopsis
- Pancreatic lipase (PLP) is an enzyme that breaks down fats, and inhibiting it could help manage obesity, leading to research on safer natural inhibitors due to side effects from traditional ones.
- The study tested the effects of extracts from Rauvolfia vomitoria leaves (aqueous, ethanolic, and methanolic) on anti-glycation, anti-inflammatory, and lipase inhibition using lab techniques to analyze the compounds' properties.
- Among the extracts, the methanolic one (MRV) showed the strongest PLP inhibition and interacted effectively with the enzyme, suggesting potential for a natural obesity treatment and insights into drug design.
Ethnotherapeutic Uses and Phytochemical Composition of L.: An Overview.
ScientificWorldJournal
February 2022
Department of Pharmacology and Therapeutics, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Article Synopsis
- Plant-derived medicines are gaining popularity in both traditional and modern medicine, particularly in developing countries, with a focus on the widespread use of a specific plant, which this review explores.
- The review collected data from numerous databases to evaluate the ethnotherapeutic applications and phytochemical composition of the plant, noting that it is predominantly used for gastrointestinal disorders and that the leaves are most commonly utilized.
- A total of 502 phytochemicals were identified in various parts of the plant, with terpenes and phenolic compounds being the most prevalent categories, highlighting the need for further pharmacological investigation of these compounds before clinical application.
Biological and Phytochemical Investigations on , a Plant Traditionally Used as Antimalarial in Guinea.
Evid Based Complement Alternat Med
September 2017
Research and Valorization Center on Medicinal Plants, Dubreka, Guinea.
is widely used as antimalarial in Guinean traditional medicine. Leaf extracts of the plant were tested for their in vitro antiprotozoal activity against and the chloroquine-sensitive Ghana strain of along with their cytotoxicity on MRC-5 cells. The methanolic extract showed the strongest antiprotozoal activity against (IC 4 g/ml), a good activity against (IC 13 g/ml), and a moderate activity against (IC 31 g/ml) along with an IC on human MRC-5 cells of 32 g/ml.
View Article and Find Full Text PDFEthnobotany, phytochemistry, toxicology and pharmacological properties of Terminalia sericea Burch. ex DC. (Combretaceae) - A review.
J Ethnopharmacol
December 2016
Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa. Electronic address:
Ethnopharmacological Reference: The use of medicinal plants in the treatment of infections is ancient. A wide variety of ethnotherapeutic properties and pharmacological actions has been attributed to Terminalia sericea. Studies by various groups of investigators reveal that it is a multipurpose medicinal plant used mostly in the treatment of diarrhoea, sexually transmitted infections, skin rashes, tuberculosis and other infections.
View Article and Find Full Text PDFWound healing activity of methanolic and aqueous extracts of Plagiochila beddomei Steph. thallus in rat model.
Indian J Exp Biol
August 2012
Plant Biochemistry and Molecular Biology Laboratory, Department of Botany, University College, Thiruvananthapuram 695 034, India.
Wound healing occurs as a fundamental response to tissue injury. Polyphenols are considered to be principle constituent to promote wound healing. Plagiochila beddomei was applied clinically by Paliyar tribes of Madurai district to treat intractable wounds.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!