AI Article Synopsis
- A 78-year-old woman was admitted to the hospital with severe acute liver failure, and tests revealed it was caused by idiopathic hypereosinophilic syndrome, as indicated by a high eosinophil count.
- She had a history of marked eosinophilia, noted six months prior to her hospitalization, and started receiving corticosteroid therapy.
- During her treatment, she experienced a duodenal perforation that was surgically repaired, and a liver biopsy showed signs of liver cell damage but also indicated improvement in liver function with continued corticosteroid therapy.
Article Abstract
A 78-year-old woman presenting with severe acute liver failure was admitted to our hospital. On screening for the etiology of acute liver failure, it was diagnosed as being due to idiopathic hypereosinophilic syndrome (eosinophil count reported as 4766/μL; 33.8% of the white blood cells). Her medical history included marked eosinophilia, as observed six months prior to this admission. Corticosteroid therapy was initiated. During the clinical course, duodenal perforation occurred but was managed promptly by appropriate surgery. A liver biopsy, following the initiation of corticosteroid therapy, revealed degenerating hepatic cells with mild eosinophilic infiltration. With corticosteroid therapy, the liver function improved.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9177379 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.8283-21 | DOI Listing |
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